Ribavarin - Revision history

ClaireLewis: Redirected page to Ribavirin

2016-10-05T04:04:15Z

Redirected page to Ribavirin

← Older revision		Revision as of 04:04, 5 October 2016
Line 1:		Line 1:
	~~==Administration==~~		#REDIRECT[[Ribavirin]]
	*Type: Antiviral- FDA approved for [[~~Hepatitis C]], severe [[RSV]] infection. Off-label use: [[herpes simplex]], [[influenza]], [[viral hemorrhagic fever]]~~
	*Dosage Forms: 200 tab, 200 cap
	*Routes of Administration: Oral, inhalation
	*Common Trade Names: Copegus, Rebetol, Ribasphere

	~~==Adult Dosing==~~
	*200-1000mg daily (dose depends on genotype and concurrent treatment with interferon)

	~~==Pediatric Dosing==~~
	*Hep C: >2 years old: 15mg/kg daily OR 400-1200mg daily
	*RSV (severe cases): 20mg/ml aerosolized over 12-18 hours x 3-7 days

	~~==Special Populations==~~
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: X
	*[[Lactation risk categories\|Lactation risk]]: Infant risk cannot be ruled out
	*Renal dosing: reduced doses for mild-moderate impairment, do not use if CrCl <50

	~~==Contraindications==~~
	*Allergy to class/drug
	*[[Autoimmune hepatitis]]
	*Coadministration with didanosine
	*Hemoglobinopathy (e.g. [[thalassemia]], [[sickle cell]])
	*[[Pregnant]] or potentially pregnant women, men who may impregnate someone
	*Renal impairment (CrCl <50)

	~~==Adverse Reactions==~~
	~~===Serious===~~
	*[[Hemolytic anemia]], [[TTP]]
	*[[Bacterial disease]]
	*[[Hepatotoxicity]]
	*[[MI]]
	*[[Suicide]]

	~~===Common===~~
	*[[Neutropenia]]
	*[[Nausea]], [[vomiting]], [[diarrhea]]
	*Asthenia, [[dizziness]], [[fatigue]]
	*Weight loss
	*[[Pruritus]]

	~~==Pharmacology==~~
	*Half-life: ~300 hours
	*Metabolism:
	*Excretion: Mostly renal

	~~==Mechanism of Action==~~
	*Mechanism not well understood

	~~==Comments==~~

	~~==See Also==~~
	*[[Viral hepatitis]]
	*[[Hepatitis C]]

	~~==References==~~
	~~<references/>~~
	~~[[Category:Pharmacology~~]]

Rossdonaldson1: /* Adverse Reactions */

2016-09-29T17:58:54Z

Adverse Reactions

← Older revision		Revision as of 17:58, 29 September 2016
Line 27:		Line 27:
	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
	*Hemolytic anemia, TTP		*[[Hemolytic anemia]], [[TTP]]
	*Bacterial disease		*[[Bacterial disease]]
	*Hepatotoxicity		*[[Hepatotoxicity]]
	*MI		*[[MI]]
	*Suicide		*[[Suicide]]

	===Common===		===Common===
	*Neutropenia		*[[Neutropenia]]
	*Nausea, vomiting, diarrhea		*[[Nausea]], [[vomiting]], [[diarrhea]]
	*Asthenia, dizziness, fatigue		*Asthenia, [[dizziness]], [[fatigue]]
	*Weight loss		*Weight loss
	*Pruritus		*[[Pruritus]]

	==Pharmacology==		==Pharmacology==

Rossdonaldson1: /* Contraindications */

2016-09-29T17:56:25Z

Contraindications

← Older revision		Revision as of 17:56, 29 September 2016
Line 19:		Line 19:
	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
	*Autoimmune hepatitis		*[[Autoimmune hepatitis]]
	*Coadministration with didanosine		*Coadministration with didanosine
	*Hemoglobinopathy (e.g. thalassemia, sickle cell)		*Hemoglobinopathy (e.g. [[thalassemia]], [[sickle cell]])
	*Pregnant or potentially pregnant women, men who may impregnate someone		*[[Pregnant]] or potentially pregnant women, men who may impregnate someone
	*Renal impairment (CrCl <50)		*Renal impairment (CrCl <50)

Kaoru: /* See Also */

2016-09-28T17:24:40Z

Kaoru: /* Administration */

2016-09-28T17:23:56Z

Administration

← Older revision		Revision as of 17:23, 28 September 2016
Line 1:		Line 1:
	==Administration==		==Administration==
	*Type: Antiviral- FDA approved for Hepatitis C, severe RSV infection. Off-label use: herpes simplex, influenza, viral hemorrhagic fever		*Type: Antiviral- FDA approved for [[Hepatitis C]], severe [[RSV]] infection. Off-label use: [[herpes simplex]], [[influenza]], [[viral hemorrhagic fever]]
	*Dosage Forms:		*Dosage Forms: 200 tab, 200 cap
	*Routes of Administration: Oral, inhalation		*Routes of Administration: Oral, inhalation
	*Common Trade Names:		*Common Trade Names: Copegus, Rebetol, Ribasphere

	==Adult Dosing==		==Adult Dosing==

ClaireLewis at 03:35, 12 September 2016

2016-09-12T03:35:29Z

← Older revision		Revision as of 03:35, 12 September 2016
Line 1:		Line 1:
	==Administration==		==Administration==
	*Type:		*Type: Antiviral- FDA approved for Hepatitis C, severe RSV infection. Off-label use: herpes simplex, influenza, viral hemorrhagic fever
	*Dosage Forms:		*Dosage Forms:
	*Routes of Administration:		*Routes of Administration: Oral, inhalation
	*Common Trade Names:		*Common Trade Names:

	==Adult Dosing==		==Adult Dosing==
			*200-1000mg daily (dose depends on genotype and concurrent treatment with interferon)

	==Pediatric Dosing==		==Pediatric Dosing==
			*Hep C: >2 years old: 15mg/kg daily OR 400-1200mg daily
			*RSV (severe cases): 20mg/ml aerosolized over 12-18 hours x 3-7 days

	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: X
	*[[Lactation risk categories\|Lactation risk]]:		*[[Lactation risk categories\|Lactation risk]]: Infant risk cannot be ruled out
	~~===~~Renal ~~Dosing===~~		*Renal dosing: reduced doses for mild-moderate impairment, do not use if CrCl <50
	*Adult:
	*Pediatric:
	~~===Hepatic Dosing===~~
	*Adult:
	*Pediatric:

	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
			*Autoimmune hepatitis
			*Coadministration with didanosine
			*Hemoglobinopathy (e.g. thalassemia, sickle cell)
			*Pregnant or potentially pregnant women, men who may impregnate someone
			*Renal impairment (CrCl <50)

	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
			*Hemolytic anemia, TTP
			*Bacterial disease
			*Hepatotoxicity
			*MI
			*Suicide
	===Common===		===Common===
			*Neutropenia
			*Nausea, vomiting, diarrhea
			*Asthenia, dizziness, fatigue
			*Weight loss
			*Pruritus

	==Pharmacology==		==Pharmacology==
	*Half-life:		*Half-life: ~300 hours
	*Metabolism:		*Metabolism:
	*Excretion:		*Excretion: Mostly renal

	==Mechanism of Action==		==Mechanism of Action==
			*Mechanism not well understood

	==Comments==		==Comments==

	==See Also==		==See Also==
			*[[Viral hepatitis]]

	==References==		==References==
	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

ClaireLewis: Created page with "==Administration== Type: Dosage Forms: Routes of Administration: Common Trade Names: ==Adult Dosing== ==Pediatric Dosing== ==Special Populations== *Drug Ratings in..."

2016-09-07T23:07:43Z

Created page with "==Administration== *Type: *Dosage Forms: *Routes of Administration: *Common Trade Names: ==Adult Dosing== ==Pediatric Dosing== ==Special Populations== *Drug Ratings in..."

New page

==Administration==
*Type:
*Dosage Forms:
*Routes of Administration:
*Common Trade Names:

==Adult Dosing==

==Pediatric Dosing==

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]:
*[[Lactation risk categories|Lactation risk]]:
===Renal Dosing===
*Adult:
*Pediatric:
===Hepatic Dosing===
*Adult:
*Pediatric:

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===

===Common===

==Pharmacology==
*Half-life:
*Metabolism:
*Excretion:

==Mechanism of Action==

==Comments==

==See Also==

==References==
<references/>
[[Category:Pharmacology]]

← Older revision		Revision as of 17:24, 28 September 2016
Line 51:		Line 51:
	==See Also==		==See Also==
	*[[Viral hepatitis]]		*[[Viral hepatitis]]
			*[[Hepatitis C]]

	==References==		==References==
	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]