Promethazine - Revision history

Danbot: Add peer-reviewed reference

2026-03-22T10:09:11Z

Add peer-reviewed reference

← Older revision		Revision as of 10:09, 22 March 2026
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	==Administration==		==Administration==
	*Type: Antiemetic; [[Phenothiazine]] Derivative; Sedative		*Type: Antiemetic; [[Phenothiazine]] Derivative; Sedative<ref>Braude D, Crandall C. Ondansetron versus promethazine to treat acute undifferentiated nausea in the ED. Acad Emerg Med. 2008;15(3):209-215. PMID 18304050</ref>
	*Dosage Forms: 12.5mg, 25mg, 50mg; 6.25mg/5 mL sol; IM; IV		*Dosage Forms: 12.5mg, 25mg, 50mg; 6.25mg/5 mL sol; IM; IV
	*Routes of Administration: Oral		*Routes of Administration: Oral

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:57:31Z

Switch SMW query from broadtable to table format for better layout with TOC

← Older revision		Revision as of 21:57, 20 March 2026
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	\|?Has Route=Route		\|?Has Route=Route
	\|?Has Population=Population		\|?Has Population=Population
	\|format=~~broadtable~~		\|format=table
	\|headers=plain		\|headers=plain
	\|mainlabel=-		\|mainlabel=-

Danbot: Add SMW Indications by Condition query table

2026-03-20T18:20:03Z

Add SMW Indications by Condition query table

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 ==Mechanism of Action==
 *nonselective antagonist of central and peripheral H1 receptors; anticholinergic
 ==See Also==

Elcatracho: /* Administration */

2021-03-06T12:55:13Z

Administration

← Older revision		Revision as of 12:55, 6 March 2021
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	==Administration==		==Administration==
	*Type: Antiemetic; [[Phenothiazine]] Derivative; Sedative		*Type: Antiemetic; [[Phenothiazine]] Derivative; Sedative
	*Dosage Forms: 12.5,25,50; 6.25/5 mL sol; IM; IV		*Dosage Forms: 12.5mg, 25mg, 50mg; 6.25mg/5 mL sol; IM; IV
	*Routes of Administration: Oral		*Routes of Administration: Oral
	*Common Trade Names: Phenadoz; Phenergan; Promethegan		*Common Trade Names: Phenadoz; Phenergan; Promethegan

ClaireLewis: /* References */

2019-09-23T21:59:31Z

References

← Older revision		Revision as of 21:59, 23 September 2019
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	<UpToDate, Micromedex>		<UpToDate, Micromedex>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:GI]]

Mholtz: Text replacement - "prn" to "PRN"

2017-07-07T10:27:32Z

Text replacement - "prn" to "PRN"

← Older revision		Revision as of 10:27, 7 July 2017
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	**Avoid other resp. depressants		**Avoid other resp. depressants

	*Nausea/vomiting: 0.25-1mg/kg PO/IM/IV q4-6h ~~prn~~;		*Nausea/vomiting: 0.25-1mg/kg PO/IM/IV q4-6h PRN;
	**Max: 25mg/dose		**Max: 25mg/dose

	*Motion sickness: 0.5mg/kg PO q12h ~~prn~~; Start: 0.5-1h before travel		*Motion sickness: 0.5mg/kg PO q12h PRN; Start: 0.5-1h before travel
	**Max: 25mg/dose; Info: use lowest effective dose		**Max: 25mg/dose; Info: use lowest effective dose
	**Avoid other resp. depressants		**Avoid other resp. depressants

Rossdonaldson1: /* Special Populations */

2017-05-17T03:42:47Z

Special Populations

← Older revision		Revision as of 03:42, 17 May 2017
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	==Special Populations==		==Special Populations==
	*Pregnancy ~~Risk Factor~~: C		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: C

	===Renal Dosing===		===Renal Dosing===

Rossdonaldson1: /* Adult Dosing */

2016-07-30T03:43:40Z

Adult Dosing

← Older revision		Revision as of 03:43, 30 July 2016
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	==Adult Dosing==		==Adult Dosing==
	*Allergic conditions: 6.25-12.5mg PO tid		*[[Allergic conditions]]: 6.25-12.5mg PO tid
	**May give additional dose of 12.5-25mg PO qhs		**May give additional dose of 12.5-25mg PO qhs

	*Nausea/vomiting: 12.5-25mg PO/IM/IV q4-6h		*[[Nausea/vomiting]]: 12.5-25mg PO/IM/IV q4-6h
	**Max: 50mg/dose PO/IM; 25mg/dose IV		**Max: 50mg/dose PO/IM; 25mg/dose IV
	**IM preferred over IV		**IM preferred over IV

Rossdonaldson1: /* Administration */

2016-07-30T03:43:18Z

Administration

← Older revision		Revision as of 03:43, 30 July 2016
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	==Administration==		==Administration==
	*Type: Antiemetic; Phenothiazine Derivative; Sedative		*Type: Antiemetic; [[Phenothiazine]] Derivative; Sedative
	*Dosage Forms: 12.5,25,50; 6.25/5 mL sol; IM; IV		*Dosage Forms: 12.5,25,50; 6.25/5 mL sol; IM; IV
	*Routes of Administration: Oral		*Routes of Administration: Oral

Neil.m.young: Text replacement - "5 mg" to "5mg"

2016-07-21T08:30:47Z

Text replacement - "5 mg" to "5mg"

← Older revision		Revision as of 08:30, 21 July 2016
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	==Adult Dosing==		==Adult Dosing==
	*Allergic conditions: 6.25-12.~~5 mg~~ PO tid		*Allergic conditions: 6.25-12.5mg PO tid
	**May give additional dose of 12.5-~~25 mg~~ PO qhs		**May give additional dose of 12.5-25mg PO qhs

	*Nausea/vomiting: 12.5-~~25 mg~~ PO/IM/IV q4-6h		*Nausea/vomiting: 12.5-25mg PO/IM/IV q4-6h
	**Max: 50mg/dose PO/IM; ~~25 mg~~/dose IV		**Max: 50mg/dose PO/IM; 25mg/dose IV
	**IM preferred over IV		**IM preferred over IV

	*Motion sickness: ~~25 mg~~ PO bid		*Motion sickness: 25mg PO bid
	**Start: 0.5-1h prior to travel		**Start: 0.5-1h prior to travel

	*Sedation: 25-50mg PO/IM/IV x1		*Sedation: 25-50mg PO/IM/IV x1
	**Max: 50mg/dose PO/IM; ~~25 mg~~/dose IV		**Max: 50mg/dose PO/IM; 25mg/dose IV
	**IM preferred over IV		**IM preferred over IV

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	===Only Approved for >2 years===		===Only Approved for >2 years===
	*Allergic conditions: 0.1mg/kg PO q6h		*Allergic conditions: 0.1mg/kg PO q6h
	**Max: 12.~~5 mg~~/dose during day, ~~25 mg~~/dose qhs		**Max: 12.5mg/dose during day, 25mg/dose qhs
	**May give additional dose of up to 0.~~5 mg~~/kg PO qhs		**May give additional dose of up to 0.5mg/kg PO qhs
	**Use lowest effective dose		**Use lowest effective dose
	**Avoid other resp. depressants		**Avoid other resp. depressants

	*Nausea/vomiting: 0.25-1mg/kg PO/IM/IV q4-6h prn;		*Nausea/vomiting: 0.25-1mg/kg PO/IM/IV q4-6h prn;
	**Max: ~~25 mg~~/dose		**Max: 25mg/dose

	*Motion sickness: 0.~~5 mg~~/kg PO q12h prn; Start: 0.5-1h before travel		*Motion sickness: 0.5mg/kg PO q12h prn; Start: 0.5-1h before travel
	**Max: ~~25 mg~~/dose; Info: use lowest effective dose		**Max: 25mg/dose; Info: use lowest effective dose
	**Avoid other resp. depressants		**Avoid other resp. depressants

	*Sedation: 12.5-~~25 mg~~ PO/IM/IV x1		*Sedation: 12.5-25mg PO/IM/IV x1
	**Max: ~~25 mg~~/dose		**Max: 25mg/dose
	**IM preferred over IV		**IM preferred over IV
	**Use lowest effective dose		**Use lowest effective dose