Prednisolone - Revision history

ClaireLewis: /* General */

2019-09-20T17:59:20Z

General

← Older revision		Revision as of 17:59, 20 September 2019
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	==General==		==General==
	*Type: [[Corticosteroid]]		*Type: [[Corticosteroid]]
	*Dosage Forms: 5; 5,15,25/5 mL		*Dosage Forms: PO (5; 5,15,25/5 mL), ophthalmic
	*Common Trade Names: Flo-Pred, Millipred, Oraped, Pedipred, Prelone, Veripred 20		*Common Trade Names: Flo-Pred, Millipred, Oraped, Pedipred, Prelone, Veripred 20

Mholtz: Text replacement - "qd" to "QD"

2017-07-07T12:14:05Z

Text replacement - "qd" to "QD"

← Older revision		Revision as of 12:14, 7 July 2017
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	==Adult Dosing==		==Adult Dosing==
	===Corticosteroid-responsive conditions===		===Corticosteroid-responsive conditions===
	*5-60mg/day PO divided qd-QID		*5-60mg/day PO divided QD-QID

	===[[Asthma]], acute===		===[[Asthma]], acute===
	*ED/hospital: 40-80mg/day PO divided qd-bid, cont. until peak flow = 70% predicted		*ED/hospital: 40-80mg/day PO divided QD-bid, cont. until peak flow = 70% predicted
	*Outpatient burst treatment: 40-60mg/day PO divided qd-bid x 3-10 days		*Outpatient burst treatment: 40-60mg/day PO divided QD-bid x 3-10 days

	===[[Asthma]], severe persistent===		===[[Asthma]], severe persistent===
	*7.5-60mg PO qd-qod		*7.5-60mg PO QD-qod

	===[[Adrenal insufficiency]]===		===[[Adrenal insufficiency]]===
	*4-5mg/m<sup>2</sup> PO qd		*4-5mg/m<sup>2</sup> PO QD

	===[[Multiple sclerosis]], acute exacerbation===		===[[Multiple sclerosis]], acute exacerbation===
	*200mg PO qd x 1 wk, then 80mg PO qod x 1 mo		*200mg PO QD x 1 wk, then 80mg PO qod x 1 mo

	===[[Alcoholic hepatitis]], acute===		===[[Alcoholic hepatitis]], acute===
	*40mg PO qd		*40mg PO QD

	==Pediatric Dosing==		==Pediatric Dosing==
	===Corticosteroid-responsive conditions===		===Corticosteroid-responsive conditions===
	*0.14-2mg/kg/day PO divided qd-QID		*0.14-2mg/kg/day PO divided QD-QID

	===[[Asthma]], acute===		===[[Asthma]], acute===
	*ED/hospital: 1-2mg/kg/day PO divided qd-bid		*ED/hospital: 1-2mg/kg/day PO divided QD-bid
	*Max: 60mg/day, cont. until peak flow = 70% predicted		*Max: 60mg/day, cont. until peak flow = 70% predicted
	*Outpatient burst treatment: 1-2mg/kg/day PO divided qd-bid x 3-10 days		*Outpatient burst treatment: 1-2mg/kg/day PO divided QD-bid x 3-10 days
	*Max: 60mg/day		*Max: 60mg/day

	===[[Asthma]], severe persistent===		===[[Asthma]], severe persistent===
	*0.25-2mg/kg PO qd-qod		*0.25-2mg/kg PO QD-qod
	*Max 60mg/day		*Max 60mg/day

	===[[Adrenal insufficiency]]===		===[[Adrenal insufficiency]]===
	*4-5mg/m^2 PO qd		*4-5mg/m^2 PO QD

	===[[Nephrotic syndrome]]===		===[[Nephrotic syndrome]]===

Mholtz: Text replacement - "qid" to "QID"

2017-07-07T10:27:46Z

Text replacement - "qid" to "QID"

← Older revision		Revision as of 10:27, 7 July 2017
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	==Adult Dosing==		==Adult Dosing==
	===Corticosteroid-responsive conditions===		===Corticosteroid-responsive conditions===
	*5-60mg/day PO divided qd-~~qid~~		*5-60mg/day PO divided qd-QID

	===[[Asthma]], acute===		===[[Asthma]], acute===
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	==Pediatric Dosing==		==Pediatric Dosing==
	===Corticosteroid-responsive conditions===		===Corticosteroid-responsive conditions===
	*0.14-2mg/kg/day PO divided qd-~~qid~~		*0.14-2mg/kg/day PO divided qd-QID

	===[[Asthma]], acute===		===[[Asthma]], acute===

Rossdonaldson1: Text replacement - "peds " to "pediatric "

2016-10-20T06:23:15Z

Text replacement - "peds " to "pediatric "

← Older revision		Revision as of 06:23, 20 October 2016
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	*cataracts		*cataracts
	*[[pancreatitis]]		*[[pancreatitis]]
	*growth suppression (long-term use, ~~peds~~ patients)		*growth suppression (long-term use, pediatric patients)
	*exophthalmos		*exophthalmos
	*[[anaphylaxis]]		*[[anaphylaxis]]

Rossdonaldson1: Text replacement - "HTN" to "hypertension"

2016-07-30T21:23:06Z

Text replacement - "HTN" to "hypertension"

← Older revision		Revision as of 21:23, 30 July 2016
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	*caution if ocular HSV		*caution if ocular HSV
	*caution if immunosuppressed		*caution if immunosuppressed
	*caution if ~~HTN~~		*caution if hypertension
	*caution if CHF		*caution if CHF
	*caution if diabetes mellitus		*caution if diabetes mellitus
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	*immunosuppression		*immunosuppression
	*infection		*infection
	*[[~~HTN~~]]		*[[hypertension]]
	*[[CHF]]		*[[CHF]]
	*[[diabetes mellitus]]		*[[diabetes mellitus]]

Neil.m.young at 17:37, 26 July 2016

2016-07-26T17:37:10Z

← Older revision		Revision as of 17:37, 26 July 2016
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	===[[Adrenal insufficiency]]===		===[[Adrenal insufficiency]]===
	*4-5mg/m^2 PO qd		*4-5mg/m<sup>2</sup> PO qd

	===[[Multiple sclerosis]], acute exacerbation===		===[[Multiple sclerosis]], acute exacerbation===

Neil.m.young: Text replacement - "5 mg" to "5mg"

2016-07-21T03:19:16Z

Text replacement - "5 mg" to "5mg"

← Older revision		Revision as of 03:19, 21 July 2016
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	===[[Adrenal insufficiency]]===		===[[Adrenal insufficiency]]===
	*4-~~5 mg~~/m^2 PO qd		*4-5mg/m^2 PO qd

	===[[Multiple sclerosis]], acute exacerbation===		===[[Multiple sclerosis]], acute exacerbation===
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	===[[Adrenal insufficiency]]===		===[[Adrenal insufficiency]]===
	*4-~~5 mg~~/m^2 PO qd		*4-5mg/m^2 PO qd

	===[[Nephrotic syndrome]]===		===[[Nephrotic syndrome]]===

Neil.m.young: Text replacement - "2 mg" to "2mg"

2016-07-21T00:09:54Z

Text replacement - "2 mg" to "2mg"

← Older revision		Revision as of 00:09, 21 July 2016
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	==Pediatric Dosing==		==Pediatric Dosing==
	===Corticosteroid-responsive conditions===		===Corticosteroid-responsive conditions===
	*0.14-~~2 mg~~/kg/day PO divided qd-qid		*0.14-2mg/kg/day PO divided qd-qid

	===[[Asthma]], acute===		===[[Asthma]], acute===
	*ED/hospital: 1-~~2 mg~~/kg/day PO divided qd-bid		*ED/hospital: 1-2mg/kg/day PO divided qd-bid
	*Max: 60mg/day, cont. until peak flow = 70% predicted		*Max: 60mg/day, cont. until peak flow = 70% predicted
	*Outpatient burst treatment: 1-~~2 mg~~/kg/day PO divided qd-bid x 3-10 days		*Outpatient burst treatment: 1-2mg/kg/day PO divided qd-bid x 3-10 days
	*Max: 60mg/day		*Max: 60mg/day

	===[[Asthma]], severe persistent===		===[[Asthma]], severe persistent===
	*0.25-~~2 mg~~/kg PO qd-qod		*0.25-2mg/kg PO qd-qod
	*Max 60mg/day		*Max 60mg/day

Neil.m.young: Text replacement - "0 mg" to "0mg"

2016-07-20T10:11:57Z

Text replacement - "0 mg" to "0mg"

← Older revision		Revision as of 10:11, 20 July 2016
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	==Adult Dosing==		==Adult Dosing==
	===Corticosteroid-responsive conditions===		===Corticosteroid-responsive conditions===
	*5-~~60 mg~~/day PO divided qd-qid		*5-60mg/day PO divided qd-qid

	===[[Asthma]], acute===		===[[Asthma]], acute===
	*ED/hospital: 40-~~80 mg~~/day PO divided qd-bid, cont. until peak flow = 70% predicted		*ED/hospital: 40-80mg/day PO divided qd-bid, cont. until peak flow = 70% predicted
	*Outpatient burst treatment: 40-~~60 mg~~/day PO divided qd-bid x 3-10 days		*Outpatient burst treatment: 40-60mg/day PO divided qd-bid x 3-10 days

	===[[Asthma]], severe persistent===		===[[Asthma]], severe persistent===
	*7.5-~~60 mg~~ PO qd-qod		*7.5-60mg PO qd-qod

	===[[Adrenal insufficiency]]===		===[[Adrenal insufficiency]]===
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	===[[Multiple sclerosis]], acute exacerbation===		===[[Multiple sclerosis]], acute exacerbation===
	*~~200 mg~~ PO qd x 1 wk, then ~~80 mg~~ PO qod x 1 mo		*200mg PO qd x 1 wk, then 80mg PO qod x 1 mo

	===[[Alcoholic hepatitis]], acute===		===[[Alcoholic hepatitis]], acute===
	*~~40 mg~~ PO qd		*40mg PO qd

	==Pediatric Dosing==		==Pediatric Dosing==
Line 30:		Line 30:
	===[[Asthma]], acute===		===[[Asthma]], acute===
	*ED/hospital: 1-2 mg/kg/day PO divided qd-bid		*ED/hospital: 1-2 mg/kg/day PO divided qd-bid
	*Max: ~~60 mg~~/day, cont. until peak flow = 70% predicted		*Max: 60mg/day, cont. until peak flow = 70% predicted
	*Outpatient burst treatment: 1-2 mg/kg/day PO divided qd-bid x 3-10 days		*Outpatient burst treatment: 1-2 mg/kg/day PO divided qd-bid x 3-10 days
	*Max: ~~60 mg~~/day		*Max: 60mg/day

	===[[Asthma]], severe persistent===		===[[Asthma]], severe persistent===
	*0.25-2 mg/kg PO qd-qod		*0.25-2 mg/kg PO qd-qod
	*Max ~~60 mg~~/day		*Max 60mg/day

	===[[Adrenal insufficiency]]===		===[[Adrenal insufficiency]]===
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	===[[Nephrotic syndrome]]===		===[[Nephrotic syndrome]]===
	*~~60 mg~~/m^2/day PO divided tid x 4 wk, then ~~40 mg~~/m^2 PO qod x 4 wk		*60mg/m^2/day PO divided tid x 4 wk, then 40mg/m^2 PO qod x 4 wk

	==Special Populations==		==Special Populations==

ClaireLewis: /* Adverse Reactions */

2016-07-15T20:31:47Z

Adverse Reactions

← Older revision		Revision as of 20:31, 15 July 2016
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	*tendon rupture		*tendon rupture
	*pseudotumor cerebri		*pseudotumor cerebri
	*ICP ~~incr.~~		*ICP increase
	*[[seizures]]		*[[seizures]]
	*glaucoma		*glaucoma
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	*edema		*edema
	*muscle weakness		*muscle weakness
	*BP ~~elevated~~		*BP elevation
	*glucose intolerance		*glucose intolerance
	*petechiae/ecchymosis		*petechiae/ecchymosis
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	*menstrual irregularities		*menstrual irregularities
	*[[hypokalemia]]		*[[hypokalemia]]
	*IOP ~~incr.~~		*IOP increase
	*impaired wound healing (long-term use)		*impaired wound healing (long-term use)
	*Cushing syndrome		*Cushing syndrome