Midodrine - Revision history

Elcatracho: /* Contraindications */

2022-01-12T16:08:49Z

Contraindications

← Older revision		Revision as of 16:08, 12 January 2022
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	*Supine hypertension		*Supine hypertension
	*Acute renal disease, urinary retention		*Acute renal disease, urinary retention
	*Pheochromocytoma		*[[Pheochromocytoma]]
	*Thyrotoxicosis		*[[Thyrotoxicosis]]
	*Caution with:		*Caution with:
	**Concomitant beta-blockers or digoxin (reflex bradycardia)		**Concomitant [[beta-blockers]] or [[digoxin]] (reflex bradycardia)
	**Concomitant use of drugs that increase BP (e.g. phenylephrine, levothyroxine, pseudoephedrine)		**Concomitant use of drugs that increase BP (e.g. [[phenylephrine]], [[levothyroxine]], [[pseudoephedrine]])
	**Concomitant MAOIs or linezolid		**Concomitant MAOIs or [[linezolid]]
	**DM		**DM
	**Renal or hepatic impairment		**Renal or hepatic impairment

Elcatracho: /* Common */

2022-01-12T16:06:26Z

Common

← Older revision		Revision as of 16:06, 12 January 2022
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	===Common===		===Common===
	*Paresthesias		*Paresthesias
	*Piloerection, pruritus, rash, erythema multiforme, flushing		*Piloerection, pruritus, rash, [[erythema multiforme]], flushing
	*Hypertension		*[[Hypertension]]
	*Urinary retention or urgency		*Urinary retention or urgency
	*Abdominal pain, nausea, xerostomia		*Abdominal pain, nausea, xerostomia
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	*Anxiety, insomnia, somnolence, weakness		*Anxiety, insomnia, somnolence, weakness
	*Confusion, dizziness		*Confusion, dizziness
	*Headache		*[[Headache]]
	*Hyperesthesia		*Hyperesthesia

Elcatracho: /* Serious */

2022-01-12T16:05:44Z

Serious

← Older revision		Revision as of 16:05, 12 January 2022
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	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
	*Bradycardia		*[[Bradycardia]]
	*~~Raised~~ ICP		*[[Elevated ICP]]

	===Common===		===Common===

ClaireLewis: /* References */

2019-09-22T23:28:22Z

References

← Older revision		Revision as of 23:28, 22 September 2019
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	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:Cardiology]]

ClaireLewis: /* Administration */

2019-09-02T16:28:58Z

Administration

← Older revision		Revision as of 16:28, 2 September 2019
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	==Administration==		==Administration==
	*Type: [[~~Vasopressor~~]], alpha-1 agonist		*Type: [[Vasopressors]], alpha-1 agonist
	*Dosage Forms:		*Dosage Forms:
	*Routes of Administration: PO		*Routes of Administration: PO

ClaireLewis: Created page with "==Administration== Type: Vasopressor, alpha-1 agonist Dosage Forms: Routes of Administration: PO Common Trade Names: ProAmatine, Orvaten ==Adult Dosing== *2.5-10mg PO..."

2019-09-02T16:28:48Z

Created page with "==Administration== *Type: Vasopressor, alpha-1 agonist *Dosage Forms: *Routes of Administration: PO *Common Trade Names: ProAmatine, Orvaten ==Adult Dosing== *2.5-10mg PO..."

New page

==Administration==
*Type: [[Vasopressor]], alpha-1 agonist
*Dosage Forms:
*Routes of Administration: PO
*Common Trade Names: ProAmatine, Orvaten

==Adult Dosing==
*2.5-10mg PO q8h

==Pediatric Dosing==
''Safety/efficacy not established''

==Special Populations==
===[[Drug pregnancy categories|Pregnancy Rating]]===
*Category C

===Lactation risk===
*Unknown if excreted in breastmilk

===Renal Dosing===
*Adult: 2.5mg PO q8h, increase as tolerated

===Hepatic Dosing===
*Adult: Use caution

==Contraindications==
*Allergy to class/drug
*Severe heart disease
*Supine hypertension
*Acute renal disease, urinary retention
*Pheochromocytoma
*Thyrotoxicosis
*Caution with:
**Concomitant beta-blockers or digoxin (reflex bradycardia)
**Concomitant use of drugs that increase BP (e.g. phenylephrine, levothyroxine, pseudoephedrine)
**Concomitant MAOIs or linezolid
**DM
**Renal or hepatic impairment
**Vision problems

==Adverse Reactions==
===Serious===
*Bradycardia
*Raised ICP

===Common===
*Paresthesias
*Piloerection, pruritus, rash, erythema multiforme, flushing
*Hypertension
*Urinary retention or urgency
*Abdominal pain, nausea, xerostomia
*Chills
*Anxiety, insomnia, somnolence, weakness
*Confusion, dizziness
*Headache
*Hyperesthesia

==Pharmacology==
*Half-life: 3-4h
*Metabolism: Enzymatic hydrolysis in systemic circulation
*Excretion: Renal

==Mechanism of Action==
*Selective alpha-1 adrenergic agonist

==Comments==

==See Also==
*[[Vasopressors]]

==References==
<references/>

[[Category:Pharmacology]]