Local anesthetics - Revision history

Kxl328: /* Background */

2021-08-27T23:21:42Z

Background

← Older revision		Revision as of 23:21, 27 August 2021
Line 3:		Line 3:
	*Esters have one "i" (tetracaine, procaine, benzocaine, etc)		*Esters have one "i" (tetracaine, procaine, benzocaine, etc)
	*Ester local anesthetics more likely to cause allergic reaction due to metabolite PABA<ref>GlobalRPH. Local Anesthetics (ester and amide-type). http://www.globalrph.com/local-anesthetics.htm.</ref>		*Ester local anesthetics more likely to cause allergic reaction due to metabolite PABA<ref>GlobalRPH. Local Anesthetics (ester and amide-type). http://www.globalrph.com/local-anesthetics.htm.</ref>
	*If pt allergic to amides and esters, consider local [[Diphenhydramine]] (Na blocker)<ref>Pavlidakey PG et al. Diphenhydramine as an Alternative Local Anesthetic Agent. J Clin Aesthet Dermatol. 2009 Oct; 2(10): 37–40.</reF>		*If patient allergic to amides and esters, consider local [[Diphenhydramine]] (Na blocker)<ref>Pavlidakey PG et al. Diphenhydramine as an Alternative Local Anesthetic Agent. J Clin Aesthet Dermatol. 2009 Oct; 2(10): 37–40.</reF>
	**Sodium channel blocker mechanism		**Sodium channel blocker mechanism
	**1-2 mL of 1% diphenhydramine at a time, to not exceed excessive sedation dose		**1-2 mL of 1% diphenhydramine at a time, to not exceed excessive sedation dose

2021-03-27T02:26:45Z

Side Effects

2020-11-29T21:31:24Z

Background

← Older revision		Revision as of 21:31, 29 November 2020
Line 3:		Line 3:
	*Esters have one "i" (tetracaine, procaine, benzocaine, etc)		*Esters have one "i" (tetracaine, procaine, benzocaine, etc)
	*Ester local anesthetics more likely to cause allergic reaction due to metabolite PABA<ref>GlobalRPH. Local Anesthetics (ester and amide-type). http://www.globalrph.com/local-anesthetics.htm.</ref>		*Ester local anesthetics more likely to cause allergic reaction due to metabolite PABA<ref>GlobalRPH. Local Anesthetics (ester and amide-type). http://www.globalrph.com/local-anesthetics.htm.</ref>
	*If pt allergic to amides and esters, consider local [[Diphenhydramine]] (Na blocker)		*If pt allergic to amides and esters, consider local [[Diphenhydramine]] (Na blocker)<ref>Pavlidakey PG et al. Diphenhydramine as an Alternative Local Anesthetic Agent. J Clin Aesthet Dermatol. 2009 Oct; 2(10): 37–40.</reF>
			**Sodium channel blocker mechanism
			**1-2 mL of 1% diphenhydramine at a time, to not exceed excessive sedation dose
			**Typical vial is 50 mg/mL, so to make 10 mg/mL:
			***10 mL NS removed from 50 mL vial
			***Add 10 mL of 50 mg/mL diphenhydramine to 40 mL of NS
			***Sedation is dose related and is similar to what would be expected for IM doses
			***Relative contraindications are the same for IM diphenhydramine administration
	{{Maximum doses of anesthetic agents}}		{{Maximum doses of anesthetic agents}}

2016-11-08T23:06:35Z

@@ Line 3: / Line 3: @@
 *Esters have one "i" (tetracaine, procaine, benzocaine, etc)
 *Ester local anesthetics more likely to cause allergic reaction due to metabolite PABA<ref>GlobalRPH. Local Anesthetics (ester and amide-type). http://www.globalrph.com/local-anesthetics.htm.</ref>
 {{Maximum doses of anesthetic agents}}
 ==See Also==

2016-03-22T15:53:34Z

Text replacement - "Category:Drugs" to "Category:Pharmacology"

2016-01-21T11:53:42Z

Sources

← Older revision		Revision as of 11:53, 21 January 2016
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	*[[Local Anesthetic Systemic Toxicity (LAST)]]		*[[Local Anesthetic Systemic Toxicity (LAST)]]

	==~~Sources~~==		==References==
	<references/>		<references/>
	[[Category:Drugs]]		[[Category:Drugs]]

2016-01-12T16:22:34Z

← Older revision		Revision as of 16:22, 12 January 2016
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	*[[Local Anesthetic Systemic Toxicity (LAST)]]		*[[Local Anesthetic Systemic Toxicity (LAST)]]

			==Sources==
			<references/>
	[[Category:Drugs]]		[[Category:Drugs]]

2016-01-12T16:21:57Z

← Older revision		Revision as of 16:21, 12 January 2016
Line 1:		Line 1:
	==Background==		==Background==
			*Am'''i'''des have two "i's" (pr'''i'''locaine, l'''i'''docaine, etc)
			*Esters have one "i" (tetracaine, procaine, benzocaine, etc)
			*Ester local anesthetics more likely to cause allergic reaction due to metabolite PABA<ref>GlobalRPH. Local Anesthetics (ester and amide-type). http://www.globalrph.com/local-anesthetics.htm.</ref>
	{{Maximum doses of anesthetic agents}}		{{Maximum doses of anesthetic agents}}

2015-02-17T19:13:58Z

Created page with "==Background== {{Maximum doses of anesthetic agents}} ==See Also== *Local Anesthetic Systemic Toxicity (LAST) Category:Drugs"

New page

==Background==
{{Maximum doses of anesthetic agents}}

==See Also==
*[[Local Anesthetic Systemic Toxicity (LAST)]]

[[Category:Drugs]]