Kidney transplant complications - Revision history

Elcatracho: /* See Also */

2021-03-08T19:57:17Z

ClaireLewis: /* References */

2019-10-16T17:12:06Z

References

← Older revision		Revision as of 17:12, 16 October 2019
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	[[Category:Renal]]		[[Category:Renal]]
			[[Category:Surgery]]

Rossdonaldson1: Text replacement - "UA" to "Urinalysis"

2016-10-02T21:17:03Z

Text replacement - "*UA" to "*Urinalysis"

← Older revision		Revision as of 21:17, 2 October 2016
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	**best prognostic marker of graft function		**best prognostic marker of graft function
	**necessary to dose some empiric antibiotics		**necessary to dose some empiric antibiotics
	*UA (for infection and signs of rejection)		*[[Urinalysis]] (for infection and signs of rejection)
	*Tacrolimus/cyclosporine levels		*Tacrolimus/cyclosporine levels
	*Infectious work-up		*Infectious work-up

ClaireLewis: /* Management */

2016-09-29T02:24:28Z

Management

← Older revision		Revision as of 02:24, 29 September 2016
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	==Management==		==Management==
	*Empiric antimicrobials for suspected infection		*Empiric antimicrobials for suspected infection
	**See [[~~Immunosupressed~~ antibiotics]]		**See [[immunocompromised antibiotics]]
	*Consult relevant transplant team		*Consult relevant transplant team
	*High-dose steroids are usual therapy for rejection		*High-dose steroids are usual therapy for rejection

ClaireLewis at 12:59, 23 September 2016

2016-09-23T12:59:19Z

@@ Line 13: / Line 13: @@
 *Widespread thrombosis
-===Early===
+===Early Complications===
 *Symptoms of infection
 *Symptoms of recurrent disease
 *Decreased urine output
@@ Line 31: / Line 31: @@
 *Hemorrhagic or non-hemorrhagic cystitis
 ==Differential Diagnosis==
 ==Evaluation==
-*Creatinine best prognostic marker of graft function
+Depending on presentation, work-up may include:
 ==Management==
 ==Disposition==

Rossdonaldson1: /* Clinical Features */

2016-08-03T04:40:41Z

Clinical Features

← Older revision		Revision as of 04:40, 3 August 2016
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	The clinical features will depend on the type of complication and the amount of time elapsed post-transplantation.		The clinical features will depend on the type of complication and the amount of time elapsed post-transplantation.

	Hyperacute Rejection		===Hyperacute Rejection===
	*Little or no urine output		*Little or no urine output
	*Widespread thrombosis		*Widespread thrombosis

	Early		===Early===
	*Symptoms of infection		*Symptoms of infection
	*Symptoms of recurrent disease		*Symptoms of recurrent disease
Line 19:		Line 19:
	*Hemorrhagic or non-hemorrhagic cystitis		*Hemorrhagic or non-hemorrhagic cystitis

	Late Acute		===Late Acute===
	*Symptoms of infection		*Symptoms of infection
	*Symptoms of recurrent disease		*Symptoms of recurrent disease
Line 25:		Line 25:
	*Hemorrhagic or non-hemorrhagic cystitis		*Hemorrhagic or non-hemorrhagic cystitis

	Late Chronic		===Late Chronic===
	*Symptoms of infection		*Symptoms of infection
	*Symptoms of recurrent disease		*Symptoms of recurrent disease

Jsitzmann: /* Clinical Features */

2016-08-01T21:32:55Z

Clinical Features

@@ Line 8: / Line 8: @@
 ==Clinical Features==
 The clinical features will depend on the type of complication and the amount of time elapsed post-transplantation.
 ==Differential Diagnosis==

Jsitzmann: /* Clinical Features */

2016-08-01T21:15:22Z

Clinical Features

@@ Line 8: / Line 8: @@
 ==Clinical Features==
 The clinical features will depend on the type of complication and the amount of time elapsed post-transplantation.
 ==Differential Diagnosis==

Jsitzmann: /* Clinical Features */

2016-08-01T21:05:49Z

Clinical Features

← Older revision		Revision as of 21:05, 1 August 2016
Line 7:		Line 7:

	==Clinical Features==		==Clinical Features==
			The clinical features will depend on the type of complication and the amount of time elapsed post-transplantation.

			*Immediate (0-1 week)
			**Acute Tubular Necrosis
			***May be post-ischemic, commonly effecting both the proximal tubules and the thick ascending limb. Or it may be immunosupresive drug induced and only effect the proximal tubules. Granular "muddy brown casts" seen on urinalysis result from death and sloughing of tubular cells.
			**Antibody mediated rejection
			***Results from donor specific antibodies including as ABO isoagglutinins.
			***Usually results in graft loss within 24 hours.
			**Embolization and Thrombosis
			***May arise with or without rejection
			***May result from hypotension, anastomotic stenosis, arterial dissection, kinking of transplanted artery, or angulation of the vein
			**Calcium Oxalate deposition
			**Delayed graft function
			***This is defined as renal failure persisting after transplantation necessitating dialysis. It my be due to post-ischemic acute tubular necrosis, volume depletion, or volume depletion.
			**Urinary bladder dysfunction
			***This complication is especially common in diabetics and may cause hydronephrosis

			*Early (1-12 weeks)
			**Acute rejection
			**Immunosuppressive Cytotoxicity
			***Usually caused by calcineurin inhibitor toxicity
			**Infection
			**Recurrence of primary disease

			*Late Acute (greater than 3 months)
			**Hypertension
			**Renal artery stenosis
			**Acute Rejection
			**Immunosuppressive cytotoxicity

			*Late Chronic (years later)
			**Chronic allograph nephropathy
			**Immunosuppressive cytotoxicity
			**

	==Differential Diagnosis==		==Differential Diagnosis==

Neil.m.young: Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-07-23T21:35:56Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

← Older revision		Revision as of 21:35, 23 July 2016
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	==Differential Diagnosis==		==Differential Diagnosis==

	==~~Diagnosis~~==		==Evaluation==
	*Creatinine best prognostic marker of graft function		*Creatinine best prognostic marker of graft function

← Older revision		Revision as of 19:57, 8 March 2021
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	==See Also==		==See Also==
	*[[Transplant complications]]		*[[Transplant complications]]
			*[[Neutropenic fever]]
			*[[Immunocompromised antibiotics]]

	==External Links==		==External Links==

Kidney transplant complications - Revision history

Elcatracho: /* See Also */

ClaireLewis: /* References */

Rossdonaldson1: Text replacement - "*UA" to "*Urinalysis"

ClaireLewis: /* Management */

ClaireLewis at 12:59, 23 September 2016

Rossdonaldson1: /* Clinical Features */

Jsitzmann: /* Clinical Features */

Jsitzmann: /* Clinical Features */

Jsitzmann: /* Clinical Features */

Neil.m.young: Text replacement - "==Diagnosis==" to "==Evaluation=="

Rossdonaldson1: Text replacement - "UA" to "Urinalysis"