Hairy oral leukoplakia - Revision history

Danbot: Remove refs with incorrect PMIDs (verified against PubMed)

2026-03-22T10:24:51Z

Remove refs with incorrect PMIDs (verified against PubMed)

← Older revision		Revision as of 10:24, 22 March 2026
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	==Background==		==Background==
	*It is caused by the [[Epstein-Barr virus]] (EBV)~~<ref>Greenspan D, Greenspan JS. Oral hairy leukoplakia: diagnosis and management. Oral Surg Oral Med Oral Pathol. 1989;67(4):396-403. PMID 2726246</ref>~~		*It is caused by the [[Epstein-Barr virus]] (EBV)
	*Most commonly seen in immunocompromised individuals, and has a high specificity for individuals with [[HIV]]/AIDs.		*Most commonly seen in immunocompromised individuals, and has a high specificity for individuals with [[HIV]]/AIDs.
	*The white plaque appearance is due to hyperkeratosis and epithelial hyperplasia.		*The white plaque appearance is due to hyperkeratosis and epithelial hyperplasia.

Danbot: Add peer-reviewed reference

2026-03-22T10:18:21Z

Add peer-reviewed reference

← Older revision		Revision as of 10:18, 22 March 2026
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	==Background==		==Background==
	*It is caused by the [[Epstein-Barr virus]] (EBV)		*It is caused by the [[Epstein-Barr virus]] (EBV)<ref>Greenspan D, Greenspan JS. Oral hairy leukoplakia: diagnosis and management. Oral Surg Oral Med Oral Pathol. 1989;67(4):396-403. PMID 2726246</ref>
	*Most commonly seen in immunocompromised individuals, and has a high specificity for individuals with [[HIV]]/AIDs.		*Most commonly seen in immunocompromised individuals, and has a high specificity for individuals with [[HIV]]/AIDs.
	*The white plaque appearance is due to hyperkeratosis and epithelial hyperplasia.		*The white plaque appearance is due to hyperkeratosis and epithelial hyperplasia.

Rossdonaldson1: Rossdonaldson1 moved page Hairy Oral Leukoplakia to Hairy oral leukoplakia

2021-05-06T18:07:47Z

Rossdonaldson1 moved page Hairy Oral Leukoplakia to Hairy oral leukoplakia

← Older revision	Revision as of 18:07, 6 May 2021
(No difference)

Elcatracho: /* Clinical Features */

2020-12-22T22:32:00Z

Clinical Features

← Older revision		Revision as of 22:32, 22 December 2020
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	*Characterized by white plaques over the lateral sides of the tongue.		*Characterized by white plaques over the lateral sides of the tongue.
	*Unlike [[oropharyngeal candidiasis]], the white plaques are unable to be scraped off.		*Unlike [[oropharyngeal candidiasis]], the white plaques are unable to be scraped off.
	*It is asymptomatic, with most patients presenting over concern for aesthetic appearance		*Unlike other forms of leukoplakia, it is NOT a precancerous lesion
			*It is asymptomatic, with most patients presenting over concern for aesthetic appearance

	==Differential Diagnosis==		==Differential Diagnosis==

ClaireLewis at 01:24, 22 October 2020

2020-10-22T01:24:22Z

← Older revision		Revision as of 01:24, 22 October 2020
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	==Background==		==Background==
	*It is caused by the Epstein-Barr ~~Virus~~ (EBV)		*It is caused by the [[Epstein-Barr virus]] (EBV)
	*Most commonly seen in immunocompromised individuals, and has a high specificity for individuals with HIV/AIDs.		*Most commonly seen in immunocompromised individuals, and has a high specificity for individuals with [[HIV]]/AIDs.
	*The white plaque appearance is due to hyperkeratosis and epithelial hyperplasia.		*The white plaque appearance is due to hyperkeratosis and epithelial hyperplasia.

	==Clinical Features==		==Clinical Features==
	*~~Hairy Oral Leukoplakia is characterized~~ by white plaques over the lateral sides of the tongue.		*Characterized by white plaques over the lateral sides of the tongue.
	*Unlike [[~~Oropharyngeal~~ candidiasis]], the white plaques are unable to be scraped off.		*Unlike [[oropharyngeal candidiasis]], the white plaques are unable to be scraped off.
	*It is asymptomatic, with most patients presenting over concern for aesthetic appearance		*It is asymptomatic, with most patients presenting over concern for aesthetic appearance

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	* The condition is benign and does not require treatment but many patients have concerns about the aesthetic appearance.		* The condition is benign and does not require treatment but many patients have concerns about the aesthetic appearance.
	* Foundation of treatment is aimed at workup and management of the often underlying concomitant immunocompromised disease process.		* Foundation of treatment is aimed at workup and management of the often underlying concomitant immunocompromised disease process.
	* High dose acyclovir can be used (4g/day), but relief is temporary and often lesions recur until immunocompromised status is reversed		* High dose [[acyclovir]] can be used (4g/day), but relief is temporary and often lesions recur until immunocompromised status is reversed

	==Disposition==		==Disposition==
	*~~Hairy Oral Leukoplakia is a benign condition and patients may be discharged home~~ unless concomitant symptoms require further work-up		*Discharge unless concomitant symptoms require further work-up

	==See Also==		==See Also==
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	*Chapple, IL; Hamburger, J (August 2000). "The significance of oral health in HIV disease". Sexually Transmitted Infections. 76 (4): 236–43. doi:10.1136/sti.76.4.236. PMC 1744197. PMID 11026876		*Chapple, IL; Hamburger, J (August 2000). "The significance of oral health in HIV disease". Sexually Transmitted Infections. 76 (4): 236–43. doi:10.1136/sti.76.4.236. PMC 1744197. PMID 11026876
	*Cherry-Peppers, G; Daniels, CO; Meeks, V; Sanders, CF; Reznik, D (February 2003). "Oral manifestations in the era of HAART". Journal of the National Medical Association. 95 (2 Suppl 2): 21S–32S. PMC 2568277. PMID 12656429.		*Cherry-Peppers, G; Daniels, CO; Meeks, V; Sanders, CF; Reznik, D (February 2003). "Oral manifestations in the era of HAART". Journal of the National Medical Association. 95 (2 Suppl 2): 21S–32S. PMC 2568277. PMID 12656429.
			[[Category:ENT]]

Alexgrohmann: Created page with "==Background== It is caused by the Epstein-Barr Virus (EBV) Most commonly seen in immunocompromised individuals, and has a high specificity for individuals with HIV/AIDs. *..."

2020-02-23T17:15:28Z

Created page with "==Background== *It is caused by the Epstein-Barr Virus (EBV) *Most commonly seen in immunocompromised individuals, and has a high specificity for individuals with HIV/AIDs. *..."

New page

==Background==
*It is caused by the Epstein-Barr Virus (EBV)
*Most commonly seen in immunocompromised individuals, and has a high specificity for individuals with HIV/AIDs.
*The white plaque appearance is due to hyperkeratosis and epithelial hyperplasia.

==Clinical Features==
*Hairy Oral Leukoplakia is characterized by white plaques over the lateral sides of the tongue.
*Unlike [[Oropharyngeal candidiasis]], the white plaques are unable to be scraped off.
*It is asymptomatic, with most patients presenting over concern for aesthetic appearance

==Differential Diagnosis==
{{Tongue DDX}}

{{DDX oral rashes and lesions}}

==Evaluation==
*Diagnosed clinically
*Consider [[HIV]] testing if no other etiology is determined or if risk factors are present

==Management==
* The condition is benign and does not require treatment but many patients have concerns about the aesthetic appearance.
* Foundation of treatment is aimed at workup and management of the often underlying concomitant immunocompromised disease process.
* High dose acyclovir can be used (4g/day), but relief is temporary and often lesions recur until immunocompromised status is reversed

==Disposition==
*Hairy Oral Leukoplakia is a benign condition and patients may be discharged home unless concomitant symptoms require further work-up

==See Also==
*[[Tongue diagnoses]]
*[[Candidiasis]]

==References==
*Chapple, IL; Hamburger, J (August 2000). "The significance of oral health in HIV disease". Sexually Transmitted Infections. 76 (4): 236–43. doi:10.1136/sti.76.4.236. PMC 1744197. PMID 11026876
*Cherry-Peppers, G; Daniels, CO; Meeks, V; Sanders, CF; Reznik, D (February 2003). "Oral manifestations in the era of HAART". Journal of the National Medical Association. 95 (2 Suppl 2): 21S–32S. PMC 2568277. PMID 12656429.