Famotidine - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:55:38Z

Switch SMW query from broadtable to table format for better layout with TOC

← Older revision		Revision as of 21:55, 20 March 2026
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	\|?Has Route=Route		\|?Has Route=Route
	\|?Has Population=Population		\|?Has Population=Population
	\|format=~~broadtable~~		\|format=table
	\|headers=plain		\|headers=plain
	\|mainlabel=-		\|mainlabel=-

Danbot: Add SMW Indications by Condition query table

2026-03-20T18:33:44Z

Add SMW Indications by Condition query table

← Older revision		Revision as of 18:33, 20 March 2026
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	==Comments==		==Comments==


			==Indications by Condition==
			''The following table is automatically generated from disease/condition pages across WikEM.''

			{{#ask:[[Has DrugName::Famotidine]]
			\|?Has Indication=Indication
			\|?Has Dose=Dose
			\|?Has Context=Context
			\|?Has Route=Route
			\|?Has Population=Population
			\|format=broadtable
			\|headers=plain
			\|mainlabel=-
			\|sort=Has Indication
			\|limit=50
			}}

Ostermayer: Prepared the page for translation

2026-01-04T22:54:34Z

Prepared the page for translation

← Older revision		Revision as of 22:54, 4 January 2026
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			<languages/>
			<translate>

	==Administration==		==Administration==
	*Type: Histamine [[H2 blocker]]
			*Type: Histamine [[Special:MyLanguage/H2 blocker\|H2 blocker]]
	*Dosage Forms: 10, 20, and 40 PO; 40/5 mL suspension		*Dosage Forms: 10, 20, and 40 PO; 40/5 mL suspension
	*Routes of Administration: PO, IV		*Routes of Administration: PO, IV
	*Common Trade Names: Pepcid, Pepcid AC		*Common Trade Names: Pepcid, Pepcid AC


	==Adult Dosing==		==Adult Dosing==

	;Active duodenal ulcer		;Active duodenal ulcer
	*40mg PO qhs x4-6 weeks		*40mg PO qhs x4-6 weeks
Line 17:		Line 23:
	*Alt dosing: 20mg IV q12 hr		*Alt dosing: 20mg IV q12 hr

	;[[GERD]]		;[[Special:MyLanguage/GERD\|GERD]]
	*20-40mg PO BID x12 weeks		*20-40mg PO BID x12 weeks
	*Alt dosing: 20mg IV q12 hr		*Alt dosing: 20mg IV q12 hr
Line 32:		Line 38:
	*20mg PO BID x 10-28 days		*20mg PO BID x 10-28 days
	*Use in combination with other medications for eradication		*Use in combination with other medications for eradication


	==Pediatric Dosing==		==Pediatric Dosing==
	;[[PUD]]
			;[[Special:MyLanguage/PUD\|PUD]]
	*1-16 years old		*1-16 years old
	**0.5-1mg/kd/day PO daily-bid		**0.5-1mg/kd/day PO daily-bid
Line 41:		Line 49:
	**Max 40mg/day		**Max 40mg/day

	;[[GERD]]		;[[Special:MyLanguage/GERD\|GERD]]
	*<3 mo		*<3 mo
	**0.5mg/kg/day PO daily		**0.5mg/kg/day PO daily
Line 51:		Line 59:
	**Alt dosing: 0.5-1mg/kg/day IV bid		**Alt dosing: 0.5-1mg/kg/day IV bid
	**Max 40mg/day		**Max 40mg/day


	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: B
	*[[Lactation risk categories\|Lactation risk]]: Probably safe		*[[Special:MyLanguage/Drug Ratings in Pregnancy\|Pregnancy Rating]]: B
			*[[Special:MyLanguage/Lactation risk categories\|Lactation risk]]: Probably safe

	===Renal Dosing===		===Renal Dosing===

	*Adult: CrCl<50: decrease dose by 50% or give q 36-48 hr; If on dialysis give after dialysis		*Adult: CrCl<50: decrease dose by 50% or give q 36-48 hr; If on dialysis give after dialysis
	*Pediatric: CrCl 10-50: decrease dose 50% or give q24 hr, CrCl<10: give q36-48 hr		*Pediatric: CrCl 10-50: decrease dose 50% or give q24 hr, CrCl<10: give q36-48 hr

	===Hepatic Dosing===		===Hepatic Dosing===

	*Adult: Not defined		*Adult: Not defined
	*Pediatric:Not defined		*Pediatric:Not defined


	==Contraindications==		==Contraindications==

	*Allergy to class/drug		*Allergy to class/drug
	*Caution in renal impairment		*Caution in renal impairment


	==Adverse Reactions==		==Adverse Reactions==


	===Serious===		===Serious===
	*[[Anaphylaxis]]
			*[[Special:MyLanguage/Anaphylaxis\|Anaphylaxis]]
	*Angioedema		*Angioedema
	*[[TEN]]		*[[Special:MyLanguage/TEN\|TEN]]
	*[[Stevens-Johnson Syndrome]]		*[[Special:MyLanguage/Stevens-Johnson Syndrome\|Stevens-Johnson Syndrome]]
	*agranulocytosis		*agranulocytosis
	*leukopenia		*leukopenia
	*[[thrombocytopenia]]		*[[Special:MyLanguage/thrombocytopenia\|thrombocytopenia]]
	*pancytopenia		*pancytopenia
	*seizures		*seizures
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	*CNS toxicity		*CNS toxicity
	*cholestatic jaundice		*cholestatic jaundice
	*[[hepatitis]]		*[[Special:MyLanguage/hepatitis\|hepatitis]]
	*interstitial pneumonia		*interstitial pneumonia
	*[[QT prolongation]]		*[[Special:MyLanguage/QT prolongation\|QT prolongation]]

	===Common===		===Common===

	*headache		*headache
	*dizziness		*dizziness
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	*taste changes		*taste changes
	*vitamin B12 deficiency		*vitamin B12 deficiency


	==Pharmacology==		==Pharmacology==

	*Half-life: 2.5-3.5 hr; >20 hr with CrCl<10		*Half-life: 2.5-3.5 hr; >20 hr with CrCl<10
	*Metabolism: minimally liver/CYP450		*Metabolism: minimally liver/CYP450
	*Excretion: urine		*Excretion: urine


	==Mechanism of Action==		==Mechanism of Action==

	*Selective histamine H2 blocker		*Selective histamine H2 blocker


	==Comments==		==Comments==


	==See Also==		==See Also==


	==References==		==References==

	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
	[[Category:GI]]		[[Category:GI]]
			</translate>

Elcatracho: /* Adverse Reactions */

2021-03-03T16:57:12Z

Adverse Reactions

← Older revision		Revision as of 16:57, 3 March 2021
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	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
	*Anaphylaxis		*[[Anaphylaxis]]
	*Angioedema		*Angioedema
	*[[TEN]]		*[[TEN]]
Line 83:		Line 83:
	*[[hepatitis]]		*[[hepatitis]]
	*interstitial pneumonia		*interstitial pneumonia
	*QT prolongation		*[[QT prolongation]]
	===Common===		===Common===
	*headache		*headache
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	*diarrhea		*diarrhea
	*taste changes		*taste changes
	*vitamin B12 deficiency		*vitamin B12 deficiency

	==Pharmacology==		==Pharmacology==

ClaireLewis at 19:46, 22 September 2019

2019-09-22T19:46:35Z

← Older revision		Revision as of 19:46, 22 September 2019
Line 1:		Line 1:
	==Administration==		==Administration==
	*Type: Histamine (H2) blocker		*Type: Histamine [[H2 blocker]]
	*Dosage Forms: 10, 20, and 40 PO; 40/5 mL suspension		*Dosage Forms: 10, 20, and 40 PO; 40/5 mL suspension
	*Routes of Administration: PO, IV		*Routes of Administration: PO, IV
Line 107:		Line 107:
	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:GI]]

Mholtz: Text replacement - " bid " to " BID "

2017-07-07T11:51:14Z

Text replacement - " bid " to " BID "

← Older revision		Revision as of 11:51, 7 July 2017
Line 8:		Line 8:
	;Active duodenal ulcer		;Active duodenal ulcer
	*40mg PO qhs x4-6 weeks		*40mg PO qhs x4-6 weeks
	*Alt dosing: 20mg PO ~~bid~~ or 20mg IV q12 hr		*Alt dosing: 20mg PO BID or 20mg IV q12 hr

	;Maintenance duodenal ulcer		;Maintenance duodenal ulcer
Line 18:		Line 18:

	;[[GERD]]		;[[GERD]]
	*20-40mg PO ~~bid~~ x12 weeks		*20-40mg PO BID x12 weeks
	*Alt dosing: 20mg IV q12 hr		*Alt dosing: 20mg IV q12 hr

Line 30:		Line 30:

	;H. pylori infection		;H. pylori infection
	*20mg PO ~~bid~~ x 10-28 days		*20mg PO BID x 10-28 days
	*Use in combination with other medications for eradication		*Use in combination with other medications for eradication

Neil.m.young: Text replacement - "0 mg" to "0mg"

2016-07-20T18:32:17Z

Text replacement - "0 mg" to "0mg"

← Older revision		Revision as of 18:32, 20 July 2016
Line 7:		Line 7:
	==Adult Dosing==		==Adult Dosing==
	;Active duodenal ulcer		;Active duodenal ulcer
	*~~40 mg~~ PO qhs x4-6 weeks		*40mg PO qhs x4-6 weeks
	*Alt dosing: ~~20 mg~~ PO bid or ~~20 mg~~ IV q12 hr		*Alt dosing: 20mg PO bid or 20mg IV q12 hr

	;Maintenance duodenal ulcer		;Maintenance duodenal ulcer
	*~~20 mg~~ PO qhs		*20mg PO qhs

	;Gastric ulcer		;Gastric ulcer
	*~~40 mg~~ PO qhs		*40mg PO qhs
	*Alt dosing: ~~20 mg~~ IV q12 hr		*Alt dosing: 20mg IV q12 hr

	;[[GERD]]		;[[GERD]]
	*20-~~40 mg~~ PO bid x12 weeks		*20-40mg PO bid x12 weeks
	*Alt dosing: ~~20 mg~~ IV q12 hr		*Alt dosing: 20mg IV q12 hr

	;Zollinger-Ellison syndrome		;Zollinger-Ellison syndrome
	*20-~~60 mg~~ PO q6 hr		*20-60mg PO q6 hr
	*Alt dosing: ~~20 mg~~ IV q12 hr		*Alt dosing: 20mg IV q12 hr
	*Max: ~~160 mg~~ PO q6 hr		*Max: 160mg PO q6 hr

	;intractable ulcer		;intractable ulcer
	*~~20 mg~~ IV q12 hr		*20mg IV q12 hr

	;H. pylori infection		;H. pylori infection
	*~~20 mg~~ PO bid x 10-28 days		*20mg PO bid x 10-28 days
	*Use in combination with other medications for eradication		*Use in combination with other medications for eradication

Line 39:		Line 39:
	**Start at 0.5mg/kg/day daily-bid		**Start at 0.5mg/kg/day daily-bid
	**Alt dosing: 0.5-1mg/kg/day IV bid		**Alt dosing: 0.5-1mg/kg/day IV bid
	**Max ~~40 mg~~/day		**Max 40mg/day

	;[[GERD]]		;[[GERD]]
Line 50:		Line 50:
	**Start 1mg/kg/day bid		**Start 1mg/kg/day bid
	**Alt dosing: 0.5-1mg/kg/day IV bid		**Alt dosing: 0.5-1mg/kg/day IV bid
	**Max ~~40 mg~~/day		**Max 40mg/day

	==Special Populations==		==Special Populations==

Neil.m.young: Text replacement - "5 mg" to "5mg"

2016-07-19T09:50:45Z

Text replacement - "5 mg" to "5mg"

← Older revision		Revision as of 09:50, 19 July 2016
Line 37:		Line 37:
	*1-16 years old		*1-16 years old
	**0.5-1mg/kd/day PO daily-bid		**0.5-1mg/kd/day PO daily-bid
	**Start at 0.~~5 mg~~/kg/day daily-bid		**Start at 0.5mg/kg/day daily-bid
	**Alt dosing: 0.5-1mg/kg/day IV bid		**Alt dosing: 0.5-1mg/kg/day IV bid
	**Max 40 mg/day		**Max 40 mg/day
Line 43:		Line 43:
	;[[GERD]]		;[[GERD]]
	*<3 mo		*<3 mo
	**0.~~5 mg~~/kg/day PO daily		**0.5mg/kg/day PO daily
	*3-12 mo		*3-12 mo
	**1mg/kg/day PO bid		**1mg/kg/day PO bid

Neil.m.young: Text replacement - "2 mg" to "2mg"

2016-07-19T06:26:37Z

Text replacement - "2 mg" to "2mg"

← Older revision		Revision as of 06:26, 19 July 2016
Line 47:		Line 47:
	**1mg/kg/day PO bid		**1mg/kg/day PO bid
	*1-16 yo		*1-16 yo
	**1-~~2 mg~~/kg/day PO bid		**1-2mg/kg/day PO bid
	**Start 1mg/kg/day bid		**Start 1mg/kg/day bid
	**Alt dosing: 0.5-1mg/kg/day IV bid		**Alt dosing: 0.5-1mg/kg/day IV bid

Neil.m.young: Text replacement - "1 mg" to "1mg"

2016-07-18T21:58:46Z

Text replacement - "1 mg" to "1mg"

← Older revision		Revision as of 21:58, 18 July 2016
Line 36:		Line 36:
	;[[PUD]]		;[[PUD]]
	*1-16 years old		*1-16 years old
	**0.5-~~1 mg~~/kd/day PO daily-bid		**0.5-1mg/kd/day PO daily-bid
	**Start at 0.5 mg/kg/day daily-bid		**Start at 0.5 mg/kg/day daily-bid
	**Alt dosing: 0.5-~~1 mg~~/kg/day IV bid		**Alt dosing: 0.5-1mg/kg/day IV bid
	**Max 40 mg/day		**Max 40 mg/day

Line 45:		Line 45:
	**0.5 mg/kg/day PO daily		**0.5 mg/kg/day PO daily
	*3-12 mo		*3-12 mo
	**~~1 mg~~/kg/day PO bid		**1mg/kg/day PO bid
	*1-16 yo		*1-16 yo
	**1-2 mg/kg/day PO bid		**1-2 mg/kg/day PO bid
	**Start ~~1 mg~~/kg/day bid		**Start 1mg/kg/day bid
	**Alt dosing: 0.5-~~1 mg~~/kg/day IV bid		**Alt dosing: 0.5-1mg/kg/day IV bid
	**Max 40 mg/day		**Max 40 mg/day