Epidemic keratoconjunctivitis - Revision history

Rossdonaldson1 at 17:13, 4 February 2026

2026-02-04T17:13:54Z

← Older revision		Revision as of 17:13, 4 February 2026
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	**Highly contagious and potentially vision-threatening<ref name="Meyer">Meyer-Rüsenberg B, Loderstädt U, Richard G, Kaulfers P-M, Gesser C. Epidemic Keratoconjunctivitis: The Current Situation and Recommendations for Prevention and Treatment. Deutsches Ärzteblatt International. 2011;108(27):475-480. doi:10.3238/arztebl.2011.0475.</ref>		**Highly contagious and potentially vision-threatening<ref name="Meyer">Meyer-Rüsenberg B, Loderstädt U, Richard G, Kaulfers P-M, Gesser C. Epidemic Keratoconjunctivitis: The Current Situation and Recommendations for Prevention and Treatment. Deutsches Ärzteblatt International. 2011;108(27):475-480. doi:10.3238/arztebl.2011.0475.</ref>
	**Transmitted via contact with infectious fluids (commonly tear fluid) on hands, tissues, etc<ref name="Meyer" />		**Transmitted via contact with infectious fluids (commonly tear fluid) on hands, tissues, etc<ref name="Meyer" />

			{{Conjunctivitis DDX}}

	==Clinical Features==		==Clinical Features==
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	==Differential Diagnosis==		==Differential Diagnosis==
	{{~~Conjunctivitis~~ DDX}}		{{Unilateral red eye DDX}}
			{{Bilateral Red Eyes}}

	==Evaluation==		==Evaluation==

Rossdonaldson1 at 19:09, 26 September 2020

2020-09-26T19:09:30Z

← Older revision		Revision as of 19:09, 26 September 2020
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	**Highly contagious and potentially vision-threatening<ref name="Meyer">Meyer-Rüsenberg B, Loderstädt U, Richard G, Kaulfers P-M, Gesser C. Epidemic Keratoconjunctivitis: The Current Situation and Recommendations for Prevention and Treatment. Deutsches Ärzteblatt International. 2011;108(27):475-480. doi:10.3238/arztebl.2011.0475.</ref>		**Highly contagious and potentially vision-threatening<ref name="Meyer">Meyer-Rüsenberg B, Loderstädt U, Richard G, Kaulfers P-M, Gesser C. Epidemic Keratoconjunctivitis: The Current Situation and Recommendations for Prevention and Treatment. Deutsches Ärzteblatt International. 2011;108(27):475-480. doi:10.3238/arztebl.2011.0475.</ref>
	**Transmitted via contact with infectious fluids (commonly tear fluid) on hands, tissues, etc<ref name="Meyer" />		**Transmitted via contact with infectious fluids (commonly tear fluid) on hands, tissues, etc<ref name="Meyer" />

	~~[[File:EKC.png\|thumb\|Subepithelial infiltrates in EKC]]~~

	==Clinical Features==		==Clinical Features==
			[[File:EKC.png\|thumb\|Subepithelial infiltrates in epidemic keratoconjunctivitis]]
	*Ranges from subclinical conjunctivitis to severe disease with superimposed bacterial infection and systemic symptoms.<ref name="Meyer" />		*Ranges from subclinical conjunctivitis to severe disease with superimposed bacterial infection and systemic symptoms.<ref name="Meyer" />
	*Can be preceded by prodrome of [[cough]], [[fever]], malaise, [[myalgia]]s, [[nausea/vomiting]]		*Can be preceded by prodrome of [[cough]], [[fever]], malaise, [[myalgia]]s, [[nausea/vomiting]]

ClaireLewis at 16:36, 5 October 2019

2019-10-05T16:36:12Z

← Older revision		Revision as of 16:36, 5 October 2019
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	==Background==		==Background==
	*Form of viral conjunctivitis that causes keratitis in addition to conjunctivitis		*Form of [[viral conjunctivitis]] that causes keratitis in addition to conjunctivitis
	*Caused by adenovirus infection that is highly contagious and tends to occur in epidemics		*Caused by [[adenovirus]] infection that is highly contagious and tends to occur in epidemics
	**Highly ~~contageous~~ and potentially vision-threatening<ref name="Meyer">Meyer-Rüsenberg B, Loderstädt U, Richard G, Kaulfers P-M, Gesser C. Epidemic Keratoconjunctivitis: The Current Situation and Recommendations for Prevention and Treatment. Deutsches Ärzteblatt International. 2011;108(27):475-480. doi:10.3238/arztebl.2011.0475.</ref>		**Highly contagious and potentially vision-threatening<ref name="Meyer">Meyer-Rüsenberg B, Loderstädt U, Richard G, Kaulfers P-M, Gesser C. Epidemic Keratoconjunctivitis: The Current Situation and Recommendations for Prevention and Treatment. Deutsches Ärzteblatt International. 2011;108(27):475-480. doi:10.3238/arztebl.2011.0475.</ref>
	**Transmitted via contact with infectious fluids (commonly tear fluid) on hands, tissues, etc<ref name="Meyer" />		**Transmitted via contact with infectious fluids (commonly tear fluid) on hands, tissues, etc<ref name="Meyer" />

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	==Clinical Features==		==Clinical Features==
	*Ranges from subclinical conjunctivitis to severe disease with superimposed bacterial infection and systemic symptoms.<ref name="Meyer" />		*Ranges from subclinical conjunctivitis to severe disease with superimposed bacterial infection and systemic symptoms.<ref name="Meyer" />
	*Can be preceded by prodrome of cough, fever, malaise, ~~myalgias~~, nausea/vomiting		*Can be preceded by prodrome of [[cough]], [[fever]], malaise, [[myalgia]]s, [[nausea/vomiting]]
	*Worsening foreign body sensation (starts near medial canthus and spreads laterally), followed by<ref name="Meyer" />:		*Worsening foreign body sensation (starts near medial canthus and spreads laterally), followed by<ref name="Meyer" />:
	**Lid swelling		**Lid swelling
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	**Itching		**Itching
	**Photophobia		**Photophobia
	**Blurred vision		**[[Blurred vision]]
	**Conjunctival injection		**Conjunctival injection
	**Papillae of inf palpebral conjunctiva		**Papillae of inf palpebral conjunctiva
	**Ipsilateral pre-auricular lymphadenopathy		**Ipsilateral pre-auricular [[lymphadenopathy]]
	*Slit lamp exam - diffuse, superficial keratitis but no corneal ulceration		*[[Slit lamp exam]] - diffuse, superficial keratitis but no corneal ulceration
	**Subepithelial infiltrates likely secondary to adenoviral antigens deposited in corneal stroma<ref name="Park">Park SJ, Jang YS, Koh TH, Kwon YA, Song SW. Development of EKC after Eximer Laser Photorefractive Surgery and Subsequent Recurrence of EKC-like Keratitis. Korean Journal of Ophthalmology : KJO. 2011;25(6):443-446. doi:10.3341/kjo.2011.25.6.443.</ref>		**Subepithelial infiltrates likely secondary to adenoviral antigens deposited in corneal stroma<ref name="Park">Park SJ, Jang YS, Koh TH, Kwon YA, Song SW. Development of EKC after Eximer Laser Photorefractive Surgery and Subsequent Recurrence of EKC-like Keratitis. Korean Journal of Ophthalmology : KJO. 2011;25(6):443-446. doi:10.3341/kjo.2011.25.6.443.</ref>
	**These lesions usually regress within 3-6 weeks, but can last for months (and cause vision impairment if within the visual field)<ref name="Meyer" />		**These lesions usually regress within 3-6 weeks, but can last for months (and cause vision impairment if within the visual field)<ref name="Meyer" />
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	==Management==		==Management==
	*~~Artifical~~ tears		*Artificial tears
	*Cool compresses		*Cool compresses
	*~~Cycloplegics~~ if photophobia is severe		*[[Cycloplegic]]s if photophobia is severe
	*Rigorous hand hygiene to prevent transmission		*Rigorous hand hygiene to prevent transmission

Neil.m.young: Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-07-22T11:23:37Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

← Older revision		Revision as of 11:23, 22 July 2016
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	{{Conjunctivitis DDX}}		{{Conjunctivitis DDX}}

	==~~Diagnosis~~==		==Evaluation==
	*Clinical diagnosis		*Clinical diagnosis

Ostermayer: Text replacement - "Category:Ophtho" to "Category:Ophthalmology"

2016-03-22T15:43:24Z

Text replacement - "Category:Ophtho" to "Category:Ophthalmology"

← Older revision		Revision as of 15:43, 22 March 2016
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	<References/>		<References/>

	[[Category:~~Ophtho~~]]		[[Category:Ophthalmology]]
	[[Category:ID]]		[[Category:ID]]

Mholtz at 23:34, 18 August 2015

2015-08-18T23:34:05Z

← Older revision		Revision as of 23:34, 18 August 2015
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	*Form of viral conjunctivitis that causes keratitis in addition to conjunctivitis		*Form of viral conjunctivitis that causes keratitis in addition to conjunctivitis
	*Caused by adenovirus infection that is highly contagious and tends to occur in epidemics		*Caused by adenovirus infection that is highly contagious and tends to occur in epidemics
	**~~Vision~~-threatening		**Highly contageous and potentially vision-threatening<ref name="Meyer">Meyer-Rüsenberg B, Loderstädt U, Richard G, Kaulfers P-M, Gesser C. Epidemic Keratoconjunctivitis: The Current Situation and Recommendations for Prevention and Treatment. Deutsches Ärzteblatt International. 2011;108(27):475-480. doi:10.3238/arztebl.2011.0475.</ref>
			**Transmitted via contact with infectious fluids (commonly tear fluid) on hands, tissues, etc<ref name="Meyer" />

	[[File:EKC.png\|thumb\|Subepithelial infiltrates in EKC]]		[[File:EKC.png\|thumb\|Subepithelial infiltrates in EKC]]

	==Clinical Features==		==Clinical Features==
	*~~Often~~ preceded by prodrome of cough, ~~high~~ fever, malaise, myalgias, nausea/vomiting		*Ranges from subclinical conjunctivitis to severe disease with superimposed bacterial infection and systemic symptoms.<ref name="Meyer" />
	*~~Usual symptoms of viral [[conjunctivitis]] plus~~:		*Can be preceded by prodrome of cough, fever, malaise, myalgias, nausea/vomiting
	**~~Foreign body sensation~~		*Worsening foreign body sensation (starts near medial canthus and spreads laterally), followed by<ref name="Meyer" />:
	**~~Photohobia~~		**Lid swelling
	**~~Chemosis~~		**Tearing
			**Itching
			**Photophobia
			**Blurred vision
			**Conjunctival injection
	**Papillae of inf palpebral conjunctiva		**Papillae of inf palpebral conjunctiva
	**Ipsilateral ~~preauricular~~ lymphadenopathy		**Ipsilateral pre-auricular lymphadenopathy
	*Slit lamp exam - diffuse, superficial keratitis but no corneal ulceration		*Slit lamp exam - diffuse, superficial keratitis but no corneal ulceration
	**Subepithelial infiltrates likely secondary to adenoviral antigens deposited in corneal stroma<ref name="Park">Park SJ, Jang YS, Koh TH, Kwon YA, Song SW. Development of EKC after Eximer Laser Photorefractive Surgery and Subsequent Recurrence of EKC-like Keratitis. Korean Journal of Ophthalmology : KJO. 2011;25(6):443-446. doi:10.3341/kjo.2011.25.6.443.</ref>		**Subepithelial infiltrates likely secondary to adenoviral antigens deposited in corneal stroma<ref name="Park">Park SJ, Jang YS, Koh TH, Kwon YA, Song SW. Development of EKC after Eximer Laser Photorefractive Surgery and Subsequent Recurrence of EKC-like Keratitis. Korean Journal of Ophthalmology : KJO. 2011;25(6):443-446. doi:10.3341/kjo.2011.25.6.443.</ref>
			**These lesions usually regress within 3-6 weeks, but can last for months (and cause vision impairment if within the visual field)<ref name="Meyer" />

	==Differential Diagnosis==		==Differential Diagnosis==
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	*Cool compresses		*Cool compresses
	*Cycloplegics if photophobia is severe		*Cycloplegics if photophobia is severe
			*Rigorous hand hygiene to prevent transmission

	==Disposition==		==Disposition==

Mholtz at 23:16, 18 August 2015

2015-08-18T23:16:27Z

← Older revision		Revision as of 23:16, 18 August 2015
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	*Caused by adenovirus infection that is highly contagious and tends to occur in epidemics		*Caused by adenovirus infection that is highly contagious and tends to occur in epidemics
	**Vision-threatening		**Vision-threatening

			[[File:EKC.png\|thumb\|Subepithelial infiltrates in EKC]]

	==Clinical Features==		==Clinical Features==
Line 12:		Line 14:
	**Papillae of inf palpebral conjunctiva		**Papillae of inf palpebral conjunctiva
	**Ipsilateral preauricular lymphadenopathy		**Ipsilateral preauricular lymphadenopathy
			*Slit lamp exam - diffuse, superficial keratitis but no corneal ulceration
			**Subepithelial infiltrates likely secondary to adenoviral antigens deposited in corneal stroma<ref name="Park">Park SJ, Jang YS, Koh TH, Kwon YA, Song SW. Development of EKC after Eximer Laser Photorefractive Surgery and Subsequent Recurrence of EKC-like Keratitis. Korean Journal of Ophthalmology : KJO. 2011;25(6):443-446. doi:10.3341/kjo.2011.25.6.443.</ref>

	==Differential Diagnosis==		==Differential Diagnosis==
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	==Diagnosis==		==Diagnosis==
	*Clinical diagnosis		*Clinical diagnosis
	**Slit Lamp - diffuse, superficial keratitis but no corneal ulceration

	==Management==		==Management==

Mholtz at 23:09, 18 August 2015

2015-08-18T23:09:42Z

← Older revision		Revision as of 23:09, 18 August 2015
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	==Background==		==Background==
	*Form of viral conjunctivitis that causes keratitis in addition to conjunctivitis		*Form of viral conjunctivitis that causes keratitis in addition to conjunctivitis
	*Vision-threatening
	*Caused by adenovirus infection that is highly contagious and tends to occur in epidemics		*Caused by adenovirus infection that is highly contagious and tends to occur in epidemics
			**Vision-threatening

	==Clinical Features==		==Clinical Features==
	*Often preceded by cough, high fever, malaise, myalgias, N/V		*Often preceded by prodrome of cough, high fever, malaise, myalgias, nausea/vomiting
	*Usual symptoms of viral conjunctivitis plus:		*Usual symptoms of viral [[conjunctivitis]] plus:
	**Foreign body sensation		**Foreign body sensation
	**Photohobia		**Photohobia
	**Chemosis		**Chemosis
	**Papillae of inf palpebral conjunctiva		**Papillae of inf palpebral conjunctiva
	**Ipsilateral preauricular ~~LAD~~		**Ipsilateral preauricular lymphadenopathy

	~~==Diagnosis==~~
	*Slit Lamp
	**Diffuse, superficial keratitis but no corneal ulceration

	==Differential Diagnosis==		==Differential Diagnosis==
	{{Conjunctivitis DDX}}		{{Conjunctivitis DDX}}

	==~~Treatment~~==		==Diagnosis==
			*Clinical diagnosis
			**Slit Lamp - diffuse, superficial keratitis but no corneal ulceration

			==Management==
	*Artifical tears		*Artifical tears
	*Cool compresses		*Cool compresses
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	==Disposition==		==Disposition==
	*~~Referral to ophthalmologist to confirm dx and decide if pt requires course of steroids~~		*Discharge with rapid ophtho follow-up.

	==See Also==		==See Also==
	*[[Conjunctivitis]]		*[[Conjunctivitis]]

	==~~Source~~==		==References==
	*Tintinalli		<References/>
	*Mahmood, Narang. Diagnosis and management of acute red eye. Emerg Med Clin N Am 2008;26

	[[Category:Ophtho]]		[[Category:Ophtho]]
	[[Category:ID]]		[[Category:ID]]

Rossdonaldson1: /* Diagnosis */

2015-01-26T18:09:37Z

Diagnosis

← Older revision		Revision as of 18:09, 26 January 2015
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	*Slit Lamp		*Slit Lamp
	**Diffuse, superficial keratitis but no corneal ulceration		**Diffuse, superficial keratitis but no corneal ulceration

			==Differential Diagnosis==
			{{Conjunctivitis DDX}}

	==Treatment==		==Treatment==

Rossdonaldson1 at 18:08, 26 January 2015

2015-01-26T18:08:24Z

← Older revision		Revision as of 18:08, 26 January 2015
Line 1:		Line 1:
	===Background===		==Background==
	*Form of viral conjunctivitis that causes keratitis in addition to conjunctivitis		*Form of viral conjunctivitis that causes keratitis in addition to conjunctivitis
	*Vision-threatening		*Vision-threatening
	*Caused by adenovirus infection that is highly contagious and tends to occur in epidemics		*Caused by adenovirus infection that is highly contagious and tends to occur in epidemics

	===Clinical Features===		==Clinical Features==
	*Often preceded by cough, high fever, malaise, myalgias, N/V		*Often preceded by cough, high fever, malaise, myalgias, N/V
	*Usual symptoms of viral conjunctivitis plus:		*Usual symptoms of viral conjunctivitis plus:
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	**Ipsilateral preauricular LAD		**Ipsilateral preauricular LAD

	===Diagnosis===		==Diagnosis==
	*Slit Lamp		*Slit Lamp
	**Diffuse, superficial keratitis but no corneal ulceration		**Diffuse, superficial keratitis but no corneal ulceration

	===Treatment===		==Treatment==
	*Artifical tears		*Artifical tears
	*Cool compresses		*Cool compresses
	*Cycloplegics if photophobia is severe		*Cycloplegics if photophobia is severe

	===Disposition===		==Disposition==
	*Referral to ophthalmologist to confirm dx and decide if pt requires course of steroids		*Referral to ophthalmologist to confirm dx and decide if pt requires course of steroids