Digoxin - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:56:37Z

Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T17:25:37Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T16:43:46Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

← Older revision		Revision as of 16:43, 20 March 2026
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	==Comments==		==Comments==


			==Indications by Condition==
			''The following table is automatically generated from disease/condition pages across WikEM.''

			{{#ask:[[Has DrugName::Digoxin]]
			\|?Has Indication=Indication
			\|?Has Dose=Dose
			\|?Has Context=Context
			\|?Has Route=Route
			\|?Has Population=Population
			\|format=broadtable
			\|headers=plain
			\|link=subject
			\|sort=Has Indication
			\|limit=50
			}}

	==See Also==		==See Also==

2022-01-06T21:17:18Z

Pharmacology

← Older revision		Revision as of 21:17, 6 January 2022
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	==Pharmacology==		==Pharmacology==
	*Half-life:		*Onset of action
	*Metabolism:		**IV = 5-30 minutes
	*Excretion:		**PO = 0.5-2 hours
	*Kinetics		*Half-life: 36-48 hours (may be increased with renal impairment)
	**Onset of action = 1.5-4hr (IV)		*Absorption: 60-80% absorption after oral administration
			*Metabolism: ~16% is converted to metabolites
			*Excretion: Almost entirely by the kidneys

	==Mechanism of Action==		==Mechanism of Action==

2022-01-06T21:10:45Z

General

← Older revision		Revision as of 21:10, 6 January 2022
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	==General==		==General==
	*Type: Cardiac glycoside; [[CHF medications]]		*Type: Cardiac glycoside; [[CHF medications]]
			*Mechanism of action- Inhibits Na+/K+ ATPase, leading to an increase in intracellular sodium that can increase cardiac contractility
	*Dosage Forms: PO, IV, IM		*Dosage Forms: PO, IV, IM
	*Common Trade Names: Digitek, Digox, Lanoxin ~~(US)~~		*Common Trade Names: Digitek, Digox, Lanoxin

	==Adult Dosing==		==Adult Dosing==

2021-02-17T18:04:39Z

Adverse Reactions

← Older revision		Revision as of 18:04, 17 February 2021
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	*GI: nausea and vomiting, diarrhea, abdominal pain		*GI: nausea and vomiting, diarrhea, abdominal pain
	*CV: Bradycardia, SA/AV block, ventr arrhythmias		*CV: Bradycardia, SA/AV block, ventr arrhythmias
			*Neuro: [[altered mental status]], visual disturbances (yellow-tinted vision)

	==Pharmacology==		==Pharmacology==

2019-09-20T23:57:12Z

References

2016-12-04T14:25:42Z

Adult Dosing

← Older revision		Revision as of 14:25, 4 December 2016
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	==Adult Dosing==		==Adult Dosing==
	*Loading dose = 0.25mg IV q2hr until effect (max total = 1.5mg)		*Loading dose = 0.25mg IV q2hr until effect (max total = 1.5mg)
	*in acute ~~afib rvr~~ with heart failure = 0.5mg IV, then 0.25mg IV q4hr until effect or max 1.5mg		*in acute [[atrial fibrillation with RVR]] with heart failure = 0.5mg IV, then 0.25mg IV q4hr until effect or max 1.5mg

	==Pediatric Dosing==		==Pediatric Dosing==

2016-12-04T14:25:01Z

General

← Older revision		Revision as of 14:25, 4 December 2016
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	==General==		==General==
	*Type: Cardiac glycoside		*Type: Cardiac glycoside; [[CHF medications]]
	*Dosage Forms: PO, IV, IM		*Dosage Forms: PO, IV, IM
	*Common Trade Names: Digitek, Digox, Lanoxin (US)		*Common Trade Names: Digitek, Digox, Lanoxin (US)

2016-12-04T14:22:51Z

Special Populations

← Older revision		Revision as of 14:22, 4 December 2016
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	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:~~FDA Pregnancy category~~ C.		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: C
	*[[Lactation risk categories\|Lactation risk]]:		*[[Lactation risk categories\|Lactation risk]]:
	*Renal Dosing		*Renal Dosing