Dicyclomine - Revision history

Danbot: Add See Also section

2026-03-22T09:10:07Z

Add See Also section

← Older revision		Revision as of 09:10, 22 March 2026
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	*Excretion: Urine ~80%, ~10% feces		*Excretion: Urine ~80%, ~10% feces
	*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not		*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not

			==See Also==
			*[[Irritable bowel syndrome]]
			*[[Anticholinergics]]
			*[[Abdominal pain]]

	==References==		==References==

Mholtz at 22:57, 30 August 2017

2017-08-30T22:57:24Z

← Older revision		Revision as of 22:57, 30 August 2017
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	*Indication: FDA approved for irritable bowel syndrome. Used off-label for cramping associated with opioid withdrawal		*Indication: FDA approved for irritable bowel syndrome. Used off-label for cramping associated with opioid withdrawal
	*Dosage Forms: PO, IM		*Dosage Forms: PO, IM
	**DO NOT GIVE IV		**'''DO NOT GIVE IV'''
	*Common Trade Names: Bentyl		*Common Trade Names: Bentyl

Mholtz at 22:57, 30 August 2017

2017-08-30T22:57:07Z

← Older revision		Revision as of 22:57, 30 August 2017
Line 4:		Line 4:
	*Dosage Forms: PO, IM		*Dosage Forms: PO, IM
	**DO NOT GIVE IV		**DO NOT GIVE IV
	*Common Trade Names: ~~Bentyl®~~		*Common Trade Names: Bentyl

	==Adult Dosing==		==Adult Dosing==
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	*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not		*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not

	==~~Sources~~==		==References==
	*McAuley DF. GlobarlRPh Inc. ANTISPASMOTICS - Bowel spasm / ~~cramping / IBS / Hypermotility. Last updated 12/04/2016. http://www.globalrph.com/antispasmotic.htm#Dicyclomine_.~~		<references/>

	[[Category:Pharmacology]]		[[Category:Pharmacology]]

Mholtz: Text replacement - "prn" to "PRN"

2017-07-07T12:07:46Z

Text replacement - "prn" to "PRN"

← Older revision		Revision as of 12:07, 7 July 2017
Line 7:		Line 7:

	==Adult Dosing==		==Adult Dosing==
	*10-20 mg PO or IM q6 ~~prn~~		*10-20 mg PO or IM q6 PRN

	==Pediatric Dosing==		==Pediatric Dosing==

ClaireLewis at 17:22, 24 December 2016

2016-12-24T17:22:38Z

← Older revision		Revision as of 17:22, 24 December 2016
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	==General==		==General==
	*Type: antispasmodic, antimuscarinic		*Type: antispasmodic, [[anticholinergics]] (antimuscarinic)
	*Indication: ~~traditionally~~ for ~~treatment of~~ irritable bowel syndrome		*Indication: FDA approved for irritable bowel syndrome. Used off-label for cramping associated with opioid withdrawal
	*Dosage Forms: PO, IM		*Dosage Forms: PO, IM
	**DO NOT GIVE IV		**DO NOT GIVE IV
Line 8:		Line 8:
	==Adult Dosing==		==Adult Dosing==
	*10-20 mg PO or IM q6 prn		*10-20 mg PO or IM q6 prn

			==Pediatric Dosing==
			''Safety/efficacy not established''

	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
			*Age <6 mo
			*Breastfeeding
			*GI obstruction
			*Obstructive uropathy
			*Reflux esophagitis
			*Severe ulcerative colitis
			*Myasthenia gravis
			*Glaucoma
			*Unstable hemodynamics

	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
	*[[Anticholinergic toxicity]]		*See [[Anticholinergic toxicity]]
			*Syncope, poor muscle tone
			*Dyspnea, apnea, respiratory arrest
			*Anaphylaxis, angioedema
			*Seizure, coma
			*Impaired sweating/thermoregulation
			*Paralytic ileus, intestinal perforation, pseudo-obstruction, toxic megacolon
			*Psychosis
			===Common===
			*Nausea, xerostomia
			*Asthenia, dizziness, somnolence, nervousness
			*Blurred vision

			==Special Populations==
			*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: B
			*Lactation: Infant risk has been demonstrated
			*Renal Dosing: not defined
			*Hepatic Dosing: not defined

	==Pharmacology==		==Pharmacology==
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	*Excretion: Urine ~80%, ~10% feces		*Excretion: Urine ~80%, ~10% feces
	*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not		*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not

	==Sources==		==Sources==
	*McAuley DF. GlobarlRPh Inc. ANTISPASMOTICS - Bowel spasm / cramping / IBS / Hypermotility. Last updated 12/04/2016. http://www.globalrph.com/antispasmotic.htm#Dicyclomine_.		*McAuley DF. GlobarlRPh Inc. ANTISPASMOTICS - Bowel spasm / cramping / IBS / Hypermotility. Last updated 12/04/2016. http://www.globalrph.com/antispasmotic.htm#Dicyclomine_.
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

Kxl328 at 13:45, 24 December 2016

2016-12-24T13:45:04Z

← Older revision		Revision as of 13:45, 24 December 2016
Line 20:		Line 20:
	*Excretion: Urine ~80%, ~10% feces		*Excretion: Urine ~80%, ~10% feces
	*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not		*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not
			==Sources==
			*McAuley DF. GlobarlRPh Inc. ANTISPASMOTICS - Bowel spasm / cramping / IBS / Hypermotility. Last updated 12/04/2016. http://www.globalrph.com/antispasmotic.htm#Dicyclomine_.
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

Kxl328: Created page with "==General== Type: antispasmodic, antimuscarinic Indication: traditionally for treatment of irritable bowel syndrome *Dosage Forms: PO, IM **DO NOT GIVE IV *Common Trade Name..."

2016-12-24T13:43:31Z

Created page with "==General== *Type: antispasmodic, antimuscarinic *Indication: traditionally for treatment of irritable bowel syndrome *Dosage Forms: PO, IM **DO NOT GIVE IV *Common Trade Name..."

New page

==General==
*Type: antispasmodic, antimuscarinic
*Indication: traditionally for treatment of irritable bowel syndrome
*Dosage Forms: PO, IM
**DO NOT GIVE IV
*Common Trade Names: Bentyl®

==Adult Dosing==
*10-20 mg PO or IM q6 prn

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===
*[[Anticholinergic toxicity]]

==Pharmacology==
*Half-life: ~2 hours
*Excretion: Urine ~80%, ~10% feces
*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not

[[Category:Pharmacology]]

Dicyclomine - Revision history

Danbot: Add See Also section

Mholtz at 22:57, 30 August 2017

Mholtz at 22:57, 30 August 2017

Mholtz: Text replacement - "prn" to "PRN"

ClaireLewis at 17:22, 24 December 2016

Kxl328 at 13:45, 24 December 2016

Kxl328: Created page with "==General== *Type: antispasmodic, antimuscarinic *Indication: traditionally for treatment of irritable bowel syndrome *Dosage Forms: PO, IM **DO NOT GIVE IV *Common Trade Name..."

Kxl328: Created page with "==General== Type: antispasmodic, antimuscarinic Indication: traditionally for treatment of irritable bowel syndrome *Dosage Forms: PO, IM **DO NOT GIVE IV *Common Trade Name..."