Central nervous system tumor (peds) - Revision history

Ostermayer at 17:20, 17 January 2026

2026-01-17T17:20:59Z

← Older revision		Revision as of 17:20, 17 January 2026
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	{{~~Peds top}} [[~~Central nervous system tumor~~]].''~~		{{PediatricPage\|Central nervous system tumor}}
	==Background==		==Background==
	*2nd most common pediatric cancer (20%)		*2nd most common pediatric cancer (20%)

Rossdonaldson1 at 22:16, 11 November 2020

2020-11-11T22:16:52Z

← Older revision		Revision as of 22:16, 11 November 2020
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	{{Peds top}} [[~~brain~~ tumor]].''		{{Peds top}} [[Central nervous system tumor]].''
	==Background==		==Background==
	*2nd most common pediatric cancer (20%)		*2nd most common pediatric cancer (20%)

Rossdonaldson1: Rossdonaldson1 moved page CNS tumors (peds) to Central nervous system tumor (peds)

2020-11-11T22:15:48Z

Rossdonaldson1 moved page CNS tumors (peds) to Central nervous system tumor (peds)

← Older revision	Revision as of 22:15, 11 November 2020
(No difference)

Rossdonaldson1 at 22:13, 11 November 2020

2020-11-11T22:13:39Z

← Older revision		Revision as of 22:13, 11 November 2020
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	~~''For adult patients, see also~~ [[brain tumor]]''		{{Peds top}} [[brain tumor]].''

	==Background==		==Background==
	*2nd most common pediatric cancer (20%)		*2nd most common pediatric cancer (20%)

Rossdonaldson1: /* Evaluation */

2020-11-11T19:27:24Z

Evaluation

← Older revision		Revision as of 19:27, 11 November 2020
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	==Evaluation==		==Evaluation==
	[[File:PMC4489064 JPN-10-159-g001.png\|thumb\|Giant parietal lobe infantile gliosarcoma in a 5-year-old child.]]		[[File:PMC4489064 JPN-10-159-g001.png\|thumb\|Giant parietal lobe infantile gliosarcoma in a 5-year-old child.]]
			[[File:PMC3560637 medscimonit-18-5-CS37-g001.png\|thumb\|Pediatric choroid plexus carcinoma.]]
	*[[Head CT]]		*[[Head CT]]

Rossdonaldson1: /* Evaluation */

2020-11-11T19:26:03Z

Evaluation

← Older revision		Revision as of 19:26, 11 November 2020
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	==Evaluation==		==Evaluation==
			[[File:PMC4489064 JPN-10-159-g001.png\|thumb\|Giant parietal lobe infantile gliosarcoma in a 5-year-old child.]]
	*[[Head CT]]		*[[Head CT]]

ClaireLewis at 00:12, 1 October 2019

2019-10-01T00:12:39Z

← Older revision		Revision as of 00:12, 1 October 2019
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	***Do NOT give if CNS lymphoma is in the differential		***Do NOT give if CNS lymphoma is in the differential
	**Elevate head of bed to 30 degrees, provide adequate sedation in intubated patients		**Elevate head of bed to 30 degrees, provide adequate sedation in intubated patients
	**Maintain cerebral perfusion (euvolemia, vasopressors if necessary)		**Maintain cerebral perfusion (euvolemia, [[vasopressors]] if necessary)
	**Consider osmotherapy (e.g. [[hypertonic saline]], [[mannitol]])		**Consider osmotherapy (e.g. [[hypertonic saline]], [[mannitol]])

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	*[[Herniation Syndromes]]		*[[Herniation Syndromes]]
	*[[Elevated ICP]]		*[[Elevated ICP]]
			*[[Cerebral edema in brain cancer]]

	==References==		==References==
	<references/>		<references/>

ClaireLewis at 18:42, 14 September 2019

2019-09-14T18:42:00Z

← Older revision		Revision as of 18:42, 14 September 2019
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	**Posterior Fossa		**Posterior Fossa
	***[[Headache]]		***[[Headache]]
	****Early morning (sleep > hypoventilation > hypercarbia > ~~incrreases~~ CNS ~~bloodflow~~ > ~~inreaced~~ ICP)		****Early morning (sleep > hypoventilation > hypercarbia > increases CNS blood flow > increased ICP)
			****Red flags also include headaches that are worse with valsalva, wakes from sleep, occur daily
	***Effortless [[vomiting]]		***Effortless [[vomiting]]
	***[[Cranial nerve palsies]] (especially 6th nerve)		***[[Cranial nerve palsies]] (especially 6th nerve)
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	**Sellar		**Sellar
	***[[Visual disturbances\|Visual changes]], hypothalamic dysfunction ([[diabetes insipidus]], stunted growth, [[hypothyroidism]])		***[[Visual disturbances\|Visual changes]], hypothalamic dysfunction ([[diabetes insipidus]], stunted growth, [[hypothyroidism]])
			*[[Increased ICP]] features
			*Features of [[elevated ICP]] (from [[Cerebral edema in brain cancer\|cerebral edema]], [[Intracranial hemorrhage\|tumor bleed]], or mass effect
			**[[Headache]] (from increased pressure on heavily innervated meninges)
			***Red flags: worse in the morning, worse with valsalva, wakes from sleep, daily
			**[[Nausea/vomiting]]
			***Also typically worse in the morning
			**[[Papilledema]], dilated optic nerve
			**Cushing's triad: [[Bradycardia]], [[hypertension]], irregular respirations
			**[[Bulging fontanelle]] in infants
			*[[Seizure]]
			*[[Altered mental status]], irritability, coma

	==Differential Diagnosis==		==Differential Diagnosis==
	{{Pediatric HA DDX}}		{{Pediatric HA DDX}}
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	==Management==		==Management==
	*[[Increased ICP]]		*[[Increased ICP]]
	**[[~~Phenytoin~~]], [[~~benzodiazepines~~]] if actively seizing		**[[Benzodiazepines]] +/- [[AEDs]] if actively seizing
	**[[Dexamethasone]] 1mg/yr of age (max 10mg)		**[[Dexamethasone]](reduce tumor capillary permeability, inflammatory cytotoxicity)- 1mg/yr of age (max 10mg)
	***Do NOT give if CNS lymphoma is in the differential		***Do NOT give if CNS lymphoma is in the differential
			**Elevate head of bed to 30 degrees, provide adequate sedation in intubated patients
			**Maintain cerebral perfusion (euvolemia, vasopressors if necessary)
			**Consider osmotherapy (e.g. [[hypertonic saline]], [[mannitol]])

	==See Also==		==See Also==

ClaireLewis at 18:37, 14 September 2019

2019-09-14T18:37:06Z

← Older revision		Revision as of 18:37, 14 September 2019
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	***[[Cranial nerve palsies]] (especially 6th nerve)		***[[Cranial nerve palsies]] (especially 6th nerve)
	**Brainstem		**Brainstem
	***~~CN deficits~~ (facial weakness, abducens palsy, dysphagia), ataxia		***[[Cranial nerve palsies]] (facial weakness, abducens palsy, dysphagia), ataxia
	**Supratentorial		**Supratentorial
	***Headache, personality change, motor [[weakness]], [[seizure]]		***[[Headache]], personality change, motor [[weakness]], [[seizure]]
	**Sellar		**Sellar
	***Visual changes, hypothalamic dysfunction (DI, stunted growth, hypothyroidism)		***[[Visual disturbances\|Visual changes]], hypothalamic dysfunction ([[diabetes insipidus]], stunted growth, [[hypothyroidism]])

	==Differential Diagnosis==		==Differential Diagnosis==
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	==Management==		==Management==
	*[[Increased ICP]]		*[[Increased ICP]]
	**Phenytoin, benzodiazepines if actively seizing		**[[Phenytoin]], [[benzodiazepines]] if actively seizing
	**[[Dexamethasone]] 1mg/yr of age (max 10mg)		**[[Dexamethasone]] 1mg/yr of age (max 10mg)
	***Do NOT give if CNS lymphoma is in the differential		***Do NOT give if CNS lymphoma is in the differential

ClaireLewis at 18:35, 14 September 2019

2019-09-14T18:35:15Z

← Older revision		Revision as of 18:35, 14 September 2019
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			''For adult patients, see also [[brain tumor]]''

	==Background==		==Background==
	*2nd most common pediatric cancer (20%)		*2nd most common pediatric cancer (20%)