View source for Methazolamide

==Administration==
*Type: Carbonic anhydrase inhibitor, [[diuretic]]
*Dosage Forms:
*Routes of Administration: PO
*Common Trade Names: Neptazane

==Adult Dosing==
*50-100mg PO BID/TID

==Pediatric Dosing==
''Safety/efficacy not established''

==Special Populations==
===[[Drug pregnancy categories|Pregnancy Rating]]===
*C

===Lactation risk===
*Not known if enters breastmilk, use caution

===Renal Dosing===
*Contraindicated in severe impairment

===Hepatic Dosing===
*Contraindicated in severe impairment

==Contraindications==
*Allergy to class/drug
*Hypokalemia
*Hyponatremia
*Hyperchloremic acidosis
*Renal/hepatic impairment,severe
*Cirrhosis
*Adrenal insufficiency
*Caution in:
**COPD
**Concomitant high-dose ASA or steroid therapy
**Hepatic insufficiency

==Adverse Reactions==
===Serious===
*SJS/TEN


===Common===
*Drowsiness
*Paresthesias
*Anorexia, nausea/vomiting
*Sulfonamide-type reactions
*Acidosis
*Electrolyte imbalance
*Glycosuria
*Hematuria
*Thrombocytopenia
*Hepatic dysfunction
*Tinnitus

==Pharmacology==
*Half-life: 14d
*Metabolism: 
*Excretion: Urine

==Mechanism of Action==
*Carbonic anhydrase inhibitor

==Comments==


==See Also==


==References==
<references/>

[[Category:Pharmacology]]