View source for Hospital acquired-Methicillin-Resistant Staphylococcus Aureus (HA-MRSA)

{{MRSA background}}

==Management==
*[[Antibiotics]]
**[[Vancomycin]] IV if severe infection/sepsis 
**[[Daptomycin]] is a poor choice for lung infection as it is inactivated by pulmonary surfactant
**[[Linezolid]]
***Indicated in severe soft tissue infections and pneumonia thought to be caused by [[CA-MRSA]] or HA-[[MRSA]]

==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Category'''
| align="center" style="background:#f0f0f0;"|'''Antibiotic'''
| align="center" style="background:#f0f0f0;"|'''[[HA-MRSA]]'''
|-
| [[Penicillins]]||[[Penicillin G]]||R
|-
| ||[[Penicillin V]]||R
|-
| ||[[Methicillin]]||R
|-
| ||[[Nafcillin]]/[[Oxacillin]]||R
|-
| ||[[Cloxacillin]]/[[Diclox.]]||R
|-
| Amino-[[Penicillins]]||[[AMP]]/[[Amox]]||R
|-
| ||[[Amox-Clav]]||R
|-
| ||[[AMP-Sulb]]||R
|-
| Anti-Pseudomonal [[Penicillins]]||[[Ticarcillin]]||R
|-
| ||[[Ticar-Clav]]||R
|-
| ||[[Pip-Tazo]]||R
|-
| ||Piperacillin||R
|-
| [[Carbapenems]]||Doripenem||R
|-
| ||[[Ertapenem]]||R
|-
| ||[[Imipenem]]||R
|-
| ||[[Meropenem]]||R
|-
| ||[[Aztreonam]]||R
|-
| [[Fluroquinolones]]||[[Ciprofloxacin]]||R
|-
| ||[[Ofloxacin]]||R
|-
| ||Pefloxacin||R
|-
| ||[[Levofloxacin]]||R
|-
| ||[[Moxifloxacin]]||I
|-
| ||Gemifloxacin||I
|-
| ||Gatifloxacin||I
|-
| 1st G [[Cephalo]]||Cefazolin||R
|-
| 2nd G. [[Cephalo]]||[[Cefotetan]]||R
|-
| ||[[Cefoxitin]]||R
|-
| ||[[Cefuroxime]]||R
|-
| 3rd/4th G. [[Cephalo]]||[[Cefotaxime]]||R
|-
| ||Cefizoxime||R
|-
| ||[[CefTRIAXone]]||R
|-
| ||Ceftaroline||S
|-
| ||[[CefTAZidime]]||R
|-
| ||[[Cefepime]]||R
|-
| Oral 1st G. [[Cephalo]]||Cefadroxil||R
|-
| ||[[Cephalexin]]||R
|-
| Oral 2nd G. [[Cephalo]]||Cefaclor/Loracarbef||R
|-
| ||Cefproxil||R
|-
| ||Cefuroxime axetil||R
|-
| Oral 3rd G. [[Cephalo]]||Cefixime||R
|-
| ||Ceftibuten||R
|-
| ||Cefpodox/Cefdinir/Cefditoren||R
|-
| [[Aminoglycosides]]||[[Gentamicin]]||R
|-
| ||Tobramycin||R
|-
| ||[[Amikacin]]||R
|-
| ||[[Chloramphenicol]]||R
|-
| ||[[Clindamycin]]||R
|-
| [[Macrolides]]||Erythromycin||R
|-
| ||[[Azithromycin]]||R
|-
| ||Clarithromycin||R
|-
| Ketolide||Telithromycin||R
|-
| Tetracyclines||[[Doxycycline]]||I
|-
| ||Minocycline||I
|-
| Glycylcycline||Tigecycline||S
|-
| ||Daptomycin||S
|-
| Glyco/Lipoclycopeptides||[[Vancomycin]]||S
|-
| ||Teicoplanin||S
|-
| ||Telavancin||S
|-
| ||Fusidic Acid||S
|-
| ||Trimethoprim||I
|-
| ||[[TMP-SMX]]||S
|-
| Urinary Agents||[[Nitrofurantoin]]||S
|-
| ||Fosfomycin||S
|-
| Other||[[Rifampin]]||S
|-
| ||[[Metronidazole]]||R
|-
| ||Quinupristin dalfoppristin||S
|-
| ||[[Linezolid]]||S
|-
| ||Colistimethate||R
|}

===Key===
{{Template:Antibacterial Spectra Key}}

==Prevention==
#good hand hygiene
#avoid sharing personal items with carriers
#wash common household items with bleach and hot water 
#wash soiled sheets, towels, clothes in hot water with bleach and dry in hot dryer
#Eradicate carriers:
##mupirocin 2%: apply to each nostril TID x 5days
##Hibiclens wash daily x 5 days
##consider oral antibiotics  


==Table Overview==
{{Clinically Relevant Bacteria}}

==See Also==
*[[Microbiology (Main)]]
*[[Staph. aureus]]

==References==
<references/>
[[Category:ID]]