View source for Anticholinergic toxicity

==Background==
[[File:Jimson_weed.png|thumb|Datura stramonium aka Jimson Weed]]
[[File:Amanita phalloides.png|thumb|''Amanita phalloides'' aka "death cap"]]
{{Anticholinergic types}}

==Clinical Features==
{{Clinical Features Anticholinergic Toxicity}}
*[[ECG]]
**Sinus tachycardia 
**QRS widening in some cases

==Differential Diagnosis==
*[[Sympathomimetic toxicity]]
**Red, dry skin and absent bowel sounds favors anticholinergic toxicity
*[[Encephalitis]]
*[[Head trauma]]
*ETOH/sedative withdrawal
*[[Neuroleptic Malignant Syndrome (NMS)]]
*Acute psychotic disorder
*[[Hypoglycemia]]

{{Toxidrome Chart}}

{{AMS and fever DDX}}

{{Anticholinergic Toxicity Treatement}}

==Disposition==
*Consider discharge for patients with mild symptoms after 6hr obs if their symptoms resolve
*Long-acting agents, plant seeds and large ingestions should have extended observation up to 24-48 hours even if asymptomatic due to decreased gastrointestinal motility
*Admit if physostigmine was given (half-life of physo is often shorter than the ingested drug)
*Patients may be cleared if symptoms do not recur within 6 hours of the last antidote dose

==See Also==
*[[Toxicology (Main)]]

==References==
<references/>
[[Category:Toxicology]]