View source for AIDS fever of unknown origin

==Background==
Sources of fever vary by stage of disease.   The CD4 count of '''< 200 × 10<sup>6</sup> cells/μL''' is very likely if the ED absolute lymphocyte count is '''< 950 × 10(6) cells/μL''' and '''less likely if the absolute lymphocyte count is > 1,700 × 10<sup>6</sup> cells/μL'''<ref>Napoli AM et al. Absolute lymphocyte count in the emergency department predicts a low CD4 count in admitted HIV-positive patients. Acad Emerg Med. 2011 Apr;18(4):385-9.</ref>

{{HIV CD4 Chart}}

===CD4 >500===
*Work-up similarly to nonimmunocompromised pts
===CD4 200-500===
*Early bacterial respiratory infection most common
===CD4 <200===
*PCP, central line infection, MAC, TB, CMV, drug fever, sinusitis
*Also consider: endocarditis, lymphoma, histo, crypto
===CD4 <100===
*Consider disseminated MAC
*Toxoplasmosis (CNS or pulmonary)

==Differential Diagnosis==
{{HIV associated conditions}}

==Diagnosis==
*CBC
*Chemistry
*LFT
*LDH
*RPR
*UA/Cx
*Blood cx
**Aerobic, anaerobic, fungal
*Crypto
*Toxo
*Coccidiodomycosis
*CXR
*Stool cx / O&P
*CT
*[[LP]]
**Cell count, protein, glucose, VDRL, cryptocoocal antigen, cytology, toxo, CMV, JC, EBV

==Management==

==Disposition==

==See Also==
*[[HIV - AIDS (Main)]]

==References==
<references/>

[[Category:ID]]